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Heeyoon Cho, Wonjoon Lee, Lucia Sobrin; Risk Factors for Depressive Symptoms in Age-related Macular Degeneration Based on the Fifth (2011) Korea National Health and Nutrition Examination Survey (KNHANES V-2).. Invest. Ophthalmol. Vis. Sci. 2014;55(13):668.
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This study was conducted to investigate factors that are associated with depressive symptoms secondary to age-related macular degeneration (AMD), using the data obtained from the Korea National Health and Nutritional Survey (KNHANES V-2) conducted in 2011.
This was a population-based, cross-sectional study. From the fifth (2011) KNHANES, 329 participants with ophthalmologist-diagnosed AMD by fundus photography reading were selected. The prevalence of depressive symptoms in this cohort was calculated. Factors associated with depressive symptoms including socioeconomic status and associated chronic diseases were investigated in multivariate regression models.
Among the total 329 subjects, 65 (19.8%) had depressive symptoms. There were 16 males (24.6%) and 49 females (75.4%). In multivariate analysis, significant factors associated with depressive symptoms were female gender (odds ratio [OR], 1.962; 95% confidence interval [CI], 1.017-3.787) and being in the “dependent” group for activities of daily living (OR, 4.792; 95% CI, 2.493-9.211).
Female gender and being dependent on others for ADLs increased the risk of depressive symptoms in this cohort of AMD subjects. Screening for depressive symptoms in East Asian AMD patients is an important component of their care.
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