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Jinling Xu, Xinping Yu; Macular choroidal thickness in unilateral ampbypic children. Invest. Ophthalmol. Vis. Sci. 2014;55(13):792.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate the choroidal thickness(CT) in amblyopes through spectral-domain optical coherence tomography (SD-OCT).
Thirty-seven children with unilateral amblyopia and 22 visually normal children were enrolled in the study. Cross-sectional images of the choroid of each of the involved eyes were obtained by SD-OCT. The CT was measured at the fovea and 8 other locations: 1mm and 2 mm superior, temporal, inferior and nasal to the fovea. We compared the chroidal thickness among amblyopic eyes, fellow eyes of the amblyopes and the eyes in control children. Age, sex, refractive error , axial length, and corrective visual acuity were also recorded.
Bilateral differences in CT between the eyes of amblyopes and visually normal controls were found. The CT in subfoveal, lmm superior , 2mm superior, 1mm inferior, 1mm nasal, 2mm nasal,1mm temporal to the fovea were found to be thicker in amblyopic eyes than in eyes in normal controls .The CT in subfoveal , 1mm superior, 2mm superior, 1mm inferior,1mm nasal, 1mm temporal to the foveal were thicker in fellow eyes of amblyopic patients than in eyes in normal controls . The CT in subfoveal and 2mm nasal to the foveal in amblyopic eyes were thicker(p=0.0022, p=0.0432) than in fellow eyes of the amblyopes. CT in subfoveal, 1mm superior, 2mm superior, 1mm inferior, 1mm nasal and 1mm temporal to the foveal were thicker in fellow eyes of amblyopic patients than in eyes in normal controls. Subfoveal CT in amblyopic eyes was negatively correlated with axial length((r=-0.501,p=0.002),but was not correlated with spherical equivalent, LOGMAR VA and age.
Chorodial thickness was found to be thicker in amblyopic eyes . Differences were also found in the choroidal thickness in both eyes of amblyopes compared with subjects with normal vision .
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