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Nina Ni, Brian J Sperling, Sadeer B Hannush; Endothelial Cell Loss After Descemet’s Stripping Automated Endothelial Keratoplasty in Glaucoma Patients With Glaucoma Drainage Devices. Invest. Ophthalmol. Vis. Sci. 2014;55(13):890.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate endothelial cell loss and graft failure rate after Descemet’s stripping automated endothelial keratoplasty (DSAEK) for corneal edema associated with endothelial dysfunction in eyes with glaucoma drainage devices.
A retrospective review of 20 cases performed by a single surgeon (S.B.H) on 17 eyes. Outcome measures included endothelial cell loss and graft failure.
With a mean follow-up of 29.7 ± 17.1 months, endothelial cell loss was 49% ± 17% at postoperative month 3, 60% ± 16% at month 6, 62% ± 20% at month 12, and 72% ± 18% at month 18. The rate of graft failure was 35%, with most of these eyes requiring repeat endothelial keratoplasty or penetrating keratoplasty.
DSAEK in eyes with corneal edema secondary to endothelial dysfunction in the presence of glaucoma drainage devices is a successful procedure for visual rehabilitation. The incidences of intermediate term endothelial cell loss and graft failure are significant.
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