June 2015
Volume 56, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2015
Anatomical and visual outcomes after Boston Keratoprosthesis type 1 in chemical burns: the Santo Domingo experience.
Author Affiliations & Notes
  • Borja Salvador Culla
    Ophthalmology, Massachusetts Eye & Ear Infirmary, Harvard Medical School, Boston, MA
  • Linette Arzeno
    Hospital Elías Santana, Santo Domingo, Dominican Republic
  • Paraskevi Evi Kolovou
    Ophthalmology, Massachusetts Eye & Ear Infirmary, Harvard Medical School, Boston, MA
  • Santiago Martínez
    Hospital Elías Santana, Santo Domingo, Dominican Republic
  • Claes H Dohlman
    Ophthalmology, Massachusetts Eye & Ear Infirmary, Harvard Medical School, Boston, MA
  • Miguel Ángel López
    Hospital Elías Santana, Santo Domingo, Dominican Republic
  • Footnotes
    Commercial Relationships Borja Salvador Culla, Boston Keratoprosthesis, Massachusetts Eye and Ear Infirmary (F); Linette Arzeno, None; Paraskevi Kolovou, Boston Keratoprosthesis, Massachusetts Eye and Ear Infirmary (F); Santiago Martínez, None; Claes Dohlman, Boston Keratoprosthesis, Massachusetts Eye and Ear Infirmary (F); Miguel Ángel López, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 1116. doi:
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      Borja Salvador Culla, Linette Arzeno, Paraskevi Evi Kolovou, Santiago Martínez, Claes H Dohlman, Miguel Ángel López; Anatomical and visual outcomes after Boston Keratoprosthesis type 1 in chemical burns: the Santo Domingo experience.. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):1116.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To describe the visual outcomes, anatomical retention and postoperative complications of patients who underwent type 1 Boston Keratoprosthesis (B-Kpro) after ocular chemical burns in the Dominican Republic.

Methods: A retrospective review of case series including 42 eyes of 36 patients with ocular chemical burn who underwent B-Kpro type 1 implantation at Hospital Elías Santana in Santo Domingo between September 2006 and October 2014 was conducted. Visual acuity, anatomical retention and the rate of postoperative complications were evaluated.

Results: The mean age of patients was 40.86 years (25-62); 34 were male while 2 were female. The causative agent was ammonia in 21 cases, hydrochloric acid in 6 cases, hydraulic fluid in 1 case, and the agent was unknown in 14 cases. The mean follow-up time was 38.45 months (median 30; range 2-98). Best corrected mean visual acuity (LogMAR) was 2.12 (+/-0.9) at first visit, 2.44 (+/-0.64) immediately prior to B-Kpro implantation, 0.71 (+/-0.61) at 1 month, 0.69 (+/-0.75) at 6 months, 0.95 (+/-0.98) at 1 year, 1.27 (+/-1.30) at 2 years, 1.53 (+/-1.43) at 3 years, 1.25 (+/-1.41) at 4 years, and 1.32 (+/-1.44) at 5 years. Anatomical retention of the first implanted B-Kpro was achieved in 90.5% of the eyes after 1 year and 78.6.3% at 2 years. The most frequent postoperative complication was the development of a posterior capsule opacification (26%), followed by glaucoma (19%) and corneal melting (17%). Other complications included hypotony (5%), extrusion (5%), retroprosthetic membrane (5%), epiretinal membrane (3%), retinal detachment (3%), hemovitreous (3%), endophthalmitis (1%), and Ahmed valve abscess (1%).

Conclusions: Our study demonstrates an excellent retention rate of the B-Kpro type 1 in chemical burns after 2 years, with a maintained improvement of the best corrected visual acuity in the majority of patients. Because these eyes are severely damaged, it is important to follow up closely these patients after B-Kpro implantation to prevent and address promptly any vision-threatening complication.

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