June 2015
Volume 56, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2015
Long Term Outcomes of Boston KPro Type I implantation in Aniridia Associated Keratopathy
Author Affiliations & Notes
  • Jose De la Cruz
    Ophthalmology, University of Illinois Eye and Ear Infirmary, Chicago, IL
  • Maria Soledad Cortina
    Ophthalmology, University of Illinois Eye and Ear Infirmary, Chicago, IL
  • Samantha L Williamson
    Ophthalmology, University of Illinois Eye and Ear Infirmary, Chicago, IL
  • Kimberly Hsu
    Ophthalmology, University of Illinois Eye and Ear Infirmary, Chicago, IL
  • Footnotes
    Commercial Relationships Jose De la Cruz, None; Maria Cortina, None; Samantha Williamson, None; Kimberly Hsu, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 1117. doi:
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    • Get Citation

      Jose De la Cruz, Maria Soledad Cortina, Samantha L Williamson, Kimberly Hsu; Long Term Outcomes of Boston KPro Type I implantation in Aniridia Associated Keratopathy. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):1117.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To evaluate the long term outcomes of aniridic patients undergoing keratoprosthesis implantation in an Interdisciplinary artificial cornea center.

Methods: Retrospective, Single Center, Case Series

Results: Eighteen Aniridic KPRO Type I (17 patients, 1 bilateral). Age: Mean 44, (SD 18): Female: Male, 13:4. KLAL prior to KPRO: 11 eyes. Survival Rate (days): Mean: 1635 days, SD: 1132 days (Min 269 days, Max 3156 days). Type of Surgery: Aphakic KPRO 10 (55%), Pseudophakic KPRO 5 (28%). Combined KPRO/PPV/Glaucoma Tube Shunt 3 (17%). Follow up: Mean 990 days, SD 692 days.Visual Acuity Pre OP (18 eyes): 20/400 (2) 11%, 20/800 (1) 5%, CF (7) 39%, HM (7) 39%, LP (1) 5%. Last Follow up BCVA: 20/60 (2) 12.5%, 20/100 (3) 18.7%, 20/250 (3) 18.7%, 20/300 (1) 6%, 20/400 (2) 12.5%, CF (1) 6%, HM (1) 6%, LP (1) 6%, NLP (2) 12.5%.•VA 20/250 or better 55%. VA 20/300 or better 61%. VA 20/400 or worse 39%. Worst than pre-op 16 % (3) (one due to trauma, one due to intraop complication choroidal heme, one due to hypotony). Complications: Retroprosthetic Membranes (RPM) (12 eyes) 67%,. Period of Time of Appearance of RPM: Mean: 293 days (SD: 511 days, Min 35 days, Max 1855 days. Sterile keratolysis/extrusion (3 eyes) 25%. Time to sterile keratolysis/extrusion: Mean: 169 days, (SD: 30 days, Min: 150 days, Max: 204 days). Extrusion preserved baseline VA after replacement (20/100, 20/250, 20/100).

Conclusions: Long term implantation of Boston KPRO provides for a viable alterrnative for visual rehabilitation in aniridia associated keratopathy. Even in cases of extrusions the eyes preserved adequate vision after re-implantation comparesd to pre-op.

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