Purchase this article with an account.
Julian Elias Maria Klaas, Sophie Burzer, Sophia Abraham, Nikolaus Feucht, Chris Lohmann, Mathias M Maier; Optical coherence tomography findings of the vitreoretinal interface in fellow eyes of patients with vitreomacular traction or full thickness macular holes. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):1228.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
We performed a retrospective, observational clinical study to evaluate the vitreoretinal interface (VRI) in fellow eyes of patients with vitreomacular traction (VMT) or full thickness macular hole (FTMH) based on spectral domain optical coherence tomography (SD-OCT) examination.
The VRI in fellow eyes of 46 patients with VMT, 12 of which had concomitant FTMH, and the VRI of 34 patients with FTMH with complete resolution of VMT was reviewed by spectral domain optical coherence tomography (Spectralis HRA+OCT, Heidelberg Engineering, Germany) for the presence of vitreomacular adhesion (VMA), VMT, and the formation of a FTMH, lamellar macular hole (LMH) or epiretinal membrane (ERM). Patients underwent complete ophthalmic evaluation, including SD-OCT at baseline and follow-up visits and were included into the VMT-group or the FTMH-group. To classify the morphology of the VRI, we used the International Vitreomacular Traction Study Classification System by Duker et al. (Ophthalmology, 2013), evaluating the baseline SD-OCT data for significant classification parameters, including size of vitreomacular adhesion, macular thickness and volume and structural changes of retinal layers.
Of 46 eyes with VMT, 16 (34,78 %) fellow eyes also showed evidence of VMT. One of the 16 had FTMH with persisting VMT. 10 (21,74%) showed formation of an ERM, of which 2 (4,26 %) demonstrated a LMH. With 8 patients (17,39 %) showing evidence of VMA, and 13 patients (28,26 %) with an unremarkable VRI, 21 fellow eyes (45,65 %) showed no pathological morphology. With regards to the 34 patients who had FTMH with complete resolution of VMT, 7 VMAs taken together with 18 unremarkable OCTs resulted in 73,53 % of fellow eyes showing a physiological VRI. 2 fellow eyes (5,88 %) demonstrated FTMHs without VMT, and 3 (8,82 %) in turn demonstrated VMT. 5 eyes (14,71 %) revealed an ERM, 2 of them concurrent with a LMH.
Our SD-OCT-based retrospective review showed that fellow eyes of patients with VMT or FTMH were at increased risk of demonstrating pathological changes in the morphology of the VRI.
This PDF is available to Subscribers Only