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Nobuhito Ishii, Takefumi Yamaguchi, Megumi Shinzawa, Daisuke Tomida, Yumiko HIrayama, Seika Den-Shimazaki, Yoshiyuki Satake, Jun Shimazaki; Surgical outcomes of bullous keratopathy secondary to argon laser iridotomy: comparison of Descemet stripping automated endothelial keratoplasty and penetrating keratoplasty. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):1562.
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© ARVO (1962-2015); The Authors (2016-present)
To assess surgical outcome of bullous keratopathy secondary to argon laser iridotomy (LI-BK) treated with eitherDescemet stripping automated endothelial keratoplasty (DSAEK) or penetrating keratoplasty (PKP).
A total of 81 subjects undergone DSAEK and 98 subjects undergone PKP for LI-BK were retrospectively analyzed. Mean age, sex, and preoperative visual acuity was similar between the two groups. Graft survival rate, endothelial cell density (ECD), best spectacle-corrected visual acuity (BSCVA), spherical equivalent (SE), and refractive astigmatism were compared between DSAEK and PKP groups at before, 1, 3, 6, 12, and 24 months following keratoplasty.<br />
The 2-years graft survival rate did not differ significantly between DSAEK and PKP groups (86.1% vs. 98.4%, P>0.05). ECD in PKP was significantly higher than that of DSAEK at 1, 3, 6, and12 months postoperatively. BSCVA in DSAEK group was significantly better than that of PKP at 1, 3, and 12 months postoperatively. While SE did not differ significantly between the DSAEK and PKP group, refractive astigmatism was significantly lower in the DSAEK group than that of PKP group throughout the observation period.
DSAEK for LI-BK showed better BSCVA and lower refractive astigmatism compared with those in PKP. However, decreases in ECD in early postoperative period were the issue to be improved in DSAEK.
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