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Benjamin Nicholson, Amrou Ali Idris, Alan D Marmorstein, Sophie J Bakri; Central Serous Chorioretinopathy: Clinical Characteristics Associated with Visual Outcomes. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):1796.
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To identify clinical characteristics associated with poor visual acuity in central serous chorioretinopathy.
All charts coded with a diagnosis of central serous chorioretinopathy between December 1, 2001 and September 31, 2013 were reviewed to confirm the diagnosis. Those with a confirmed diagnosis and at least two office visits over a minimum one month follow-up period were included, and the subjects’ charts were reviewed retrospectively. Multivariate logistic regression analyses were performed to assess the relationship between several clinical characteristics and final visual acuity.
353 subjects were confirmed to have central serous chorioretinopathy. Of these, 258 had a minimum of two clinical assessments and adequate follow-up. Multivariate analysis showed that the following clinical factors were significantly associated with worse final visual acuity: older age at diagnosis, a history of treatment with photodynamic therapy, choroidal neovascularization, hypertension, and a history of either prostate cancer or benign prostatic hypertrophy. Diabetes mellitus was associated with better final visual acuity. In an a subgroup analysis of 151 subjects with at least one year of follow-up, the following factors were significantly associated with worsening of visual acuity over the study period: choroidal neovascularization, use of a psychiatric medication at presentation, hypertension, and gastroesophageal reflux disease.
Poor visual outcomes in central serous chorioretinopathy are associated with older age at diagnosis, choroidal neovascularization, hypertension, and a history of prostate disease. Several clinical characteristics that have been identified as risk factors for developing central serous also appear to be associated with worse visual outcomes.
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