June 2015
Volume 56, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2015
Irido-corneal angle and fundus documentation using a novel dual-mode imaging probe
Author Affiliations & Notes
  • Baskaran Mani
    Glaucoma, Singapore Eye Research Institute and Singapore National Eye Centre, Singapore, Singapore
    Ophthalmology, Yong Loo Lin School of medicine, NUS, Singapore, Singapore
  • Shinoj VK
    School of Mechanical and Aerospace Engineering, Center for Optical and Laser Engineering, Nanyang Technological University, Singapore, Singapore
  • Murukeshan VM
    School of Mechanical and Aerospace Engineering, Center for Optical and Laser Engineering, Nanyang Technological University, Singapore, Singapore
  • Tin Aung
    Glaucoma, Singapore Eye Research Institute and Singapore National Eye Centre, Singapore, Singapore
    Ophthalmology, Yong Loo Lin School of medicine, NUS, Singapore, Singapore
  • Footnotes
    Commercial Relationships Baskaran Mani, Singapore Eye Research Institute (P); Shinoj VK, Nanyang Technological University (P); Murukeshan VM, Nanyang Technological University (P); Tin Aung, Singapore Eye Research Institute (P)
  • Footnotes
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Investigative Ophthalmology & Visual Science June 2015, Vol.56, 1953. doi:
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    • Get Citation

      Baskaran Mani, Shinoj VK, Murukeshan VM, Tin Aung; Irido-corneal angle and fundus documentation using a novel dual-mode imaging probe. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):1953.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose
 

To evaluate a novel hand-held probe capable of dual mode (optical and infrared) imaging of the irido-corneal angle and fundus in a pre-clinical setting.

 
Methods
 

We have designed and developed a novel hand-held probe integrating a miniaturized charge-coupled device (CCD) video camera, light emitting diode (LED) light source and near infrared light source with specifications to capture the irido-corneal angle images and posterior segment images (Figure 1). The field of view for the camera was set at 140° for the irido-corneal angle. This dual mode probe was tested in a preclinical setting for imaging the angle and fundus in rabbits and non-human primates (NHP).

 
Results
 

The irido-corneal angle (Figure 2a - in rabbits; 2b - in NHP) and the fundus images (optic nerve head and posterior pole, Figure 2c) were captured successfully in rabbits using contact procedure with an ophthalmic gel interface. Approximately 100° of the iridocorneal angle and 60° of the posterior fundus image can be captured using the probe. The near infrared image corresponding to the angle image could be captured by alternating the light source without changing the probe position (Figure 3a and 3b).

 
Conclusions
 

We have successfully demonstrated the capabilities of a dual mode novel hand-held probe for imaging the irido-corneal angle and fundus using contact procedure. This probe can be used with the slit-lamp light source or during surgical procedures for inexpensive documentation of the angle and fundus images. Further refinement is needed for improving ease of image capture and image quality.  

 
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