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Baskaran Mani, Shinoj VK, Murukeshan VM, Tin Aung; Irido-corneal angle and fundus documentation using a novel dual-mode imaging probe. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):1953.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate a novel hand-held probe capable of dual mode (optical and infrared) imaging of the irido-corneal angle and fundus in a pre-clinical setting.
We have designed and developed a novel hand-held probe integrating a miniaturized charge-coupled device (CCD) video camera, light emitting diode (LED) light source and near infrared light source with specifications to capture the irido-corneal angle images and posterior segment images (Figure 1). The field of view for the camera was set at 140° for the irido-corneal angle. This dual mode probe was tested in a preclinical setting for imaging the angle and fundus in rabbits and non-human primates (NHP).
The irido-corneal angle (Figure 2a - in rabbits; 2b - in NHP) and the fundus images (optic nerve head and posterior pole, Figure 2c) were captured successfully in rabbits using contact procedure with an ophthalmic gel interface. Approximately 100° of the iridocorneal angle and 60° of the posterior fundus image can be captured using the probe. The near infrared image corresponding to the angle image could be captured by alternating the light source without changing the probe position (Figure 3a and 3b).
We have successfully demonstrated the capabilities of a dual mode novel hand-held probe for imaging the irido-corneal angle and fundus using contact procedure. This probe can be used with the slit-lamp light source or during surgical procedures for inexpensive documentation of the angle and fundus images. Further refinement is needed for improving ease of image capture and image quality.
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