June 2015
Volume 56, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2015
Three-dimensional morphometrical study of the iris by swept source anterior segment optical coherence tomography in caucasian population
Author Affiliations & Notes
  • Alessandro Invernizzi
    Eye Clinic, Luigi Sacco Hospital, University of Milan, Rho, Italy
    Department of Clinical Sciences and Community Health, Ophthalmological Unit, IRCCS-Cà Granda Foundation - Ospedale Maggiore Policlinico - University of Milan, Milan, Italy
  • Piero Giardini
    Eye Clinic, Luigi Sacco Hospital, University of Milan, Rho, Italy
  • Mario V Cigada
    Eye Clinic, Luigi Sacco Hospital, University of Milan, Rho, Italy
  • Francesco Viola
    Department of Clinical Sciences and Community Health, Ophthalmological Unit, IRCCS-Cà Granda Foundation - Ospedale Maggiore Policlinico - University of Milan, Milan, Italy
  • Giovanni Staurenghi
    Eye Clinic, Luigi Sacco Hospital, University of Milan, Rho, Italy
  • Footnotes
    Commercial Relationships Alessandro Invernizzi, None; Piero Giardini, None; Mario Cigada, None; Francesco Viola, None; Giovanni Staurenghi, Heidelberg Engineering (C), Optovue (S), Zeiss (C)
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 1955. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to Subscribers Only
      Sign In or Create an Account ×
    • Get Citation

      Alessandro Invernizzi, Piero Giardini, Mario V Cigada, Francesco Viola, Giovanni Staurenghi; Three-dimensional morphometrical study of the iris by swept source anterior segment optical coherence tomography in caucasian population. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):1955.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose: to analyze in vivo three-dimensional iris morphology (thickness/width/volume and pupil size) by swept source anterior segment optical coherence tomography (SS-ASOCT) and to find an eventual correlation with different influencing factors in caucasian population.

Methods: Consecutive healthy emmetropic (refractive error spherical equivalent between ± 3 Diopters) volunteers underwent standardized anterior segment photography to assess iris color and grade it. SS-ASOCT images of the enrolled eye were also obtained. Morphometric datas of the iris comprising volume, thickness, width and pupil size were calculated by OCT images analysis. Sectorial variations of morphometric datas among the main 4 sectors of the iris (superior,nasal,inferior,temporal) were assessed. Relationships between iris morphology and iris color, subject age and gender were studied.

Results: 135 eyes from 135 subjects (57 males and 78 females) fulfilled the inclusion criteria and were enrolled in the study. Mean age was 49±17 years (range 22-82). All the morphometric parameters of the iris analyzed in the study significantly change among the different sectors (all p<0.0001). Iris total volume and mean thickness significantly changed depending on the color (p<0.0001 and p=0.0384 respectively) with an increasing trend directly correlated with iris darkening. No correlation was found between iris color and width or pupil diameter. Age did not affect iris volume or thickness, whereas a significant (rs=0.52) increase in iris width was found with aging. In contrast pupil diameter significantly decreased (rs=-0.58) with subject aging. No correlations were found between sex and iris volume or thickness. Iris width significantly grater (p=0.007) in males. Pupil diameter did not change among genders.

Conclusions: Morphology of the iris in caucasian population follows constant rules in sectorial variations that can be applied to identify pathological changes in single subjects. Iris volume and thickness differently from iris width and pupil diameter are influenced by iris color. Iris width and pupil size change with aging. Males have wider iris than females.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×