June 2015
Volume 56, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2015
Feasibility Study in Normal Children of a Liquid Crystal Spectacle Filter (LCSF) for Potential Treatment of Amblyopia
Author Affiliations & Notes
  • Megan Cochran
    Akron Children's Hospital, Akron, OH
    Ohio University Heritage College of Osteopathic Medicine, Athens, OH
  • Richard W Hertle
    Akron Children's Hospital, Akron, OH
  • Paul Luchette
    Alpha Micron, Kent, OH
  • Kajal Jassemnejad
    Alpha Micron, Kent, OH
  • Sandip Bhatta
    Alpha Micron, Kent, OH
  • Tamas Kosa
    Alpha Micron, Kent, OH
  • Bahman Taheri
    Alpha Micron, Kent, OH
  • Volodymyr Bodnar
    Alpha Micron, Kent, OH
  • Footnotes
    Commercial Relationships Megan Cochran, None; Richard Hertle, None; Paul Luchette, Alpha Micron (E); Kajal Jassemnejad, Alpha Micron (E); Sandip Bhatta, Alpha Micron (E); Tamas Kosa, Alpha Micron (E); Bahman Taheri, Alpha Micron (E); Volodymyr Bodnar, Alpha Micron (E)
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 2187. doi:
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      Megan Cochran, Richard W Hertle, Paul Luchette, Kajal Jassemnejad, Sandip Bhatta, Tamas Kosa, Bahman Taheri, Volodymyr Bodnar; Feasibility Study in Normal Children of a Liquid Crystal Spectacle Filter (LCSF) for Potential Treatment of Amblyopia. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):2187.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose
 

To evaluate a new LCSF device applied to commercial eyeware for both comfort and the potential to reduce visual acuity

 
Methods
 

AlphaMicron Inc. Kent, Ohio, has developed a liquid crystal system designed specifically for eyewear which uses a polymer liquid crystal mixture consisting of "guest" monomers in a liquid crystal "host". This mixture is sandwiched between two curved flexible plastic substrates coated with transparent electrodes. By applying voltage to the substrates, the electro-optic response of the liquid crystal mixture is used to control the opacity of the device. The voltage is applied manually with a touch of a button or automatically through a sensor, providing instantaneous control over transmission. 20 normal children ages 7-10 were testing while wearing the LCSF. The amount of light transmission measure as a voltage was correlated to monocular and binocular visual acuity degradation using the PEDIG acuity testing paradigm.

 
Results
 

The LCSF is successfully able to depress visual acuity in a linear fashion by changing the “haze” or light transmission function in a stepwise fashion from 20/20 to light perception.

 
Conclusions
 

The LCSF filter may provide multiple benefits in the treatment of, including; ease of application to commercially available eyeware, cosmetic appeal, comfort, versatility in occlusion dosage and the potential to improve adherence.  

 
This is the LCSF prototype showing full light transmission above and no light transmission below.
 
This is the LCSF prototype showing full light transmission above and no light transmission below.
 
 
This curve shows the relationship between light transmission and visual acuity.
 
This curve shows the relationship between light transmission and visual acuity.

 
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