June 2015
Volume 56, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2015
Istent implantation combined with phacoemulsification compared to phacoemulsification alone in primary angle closure and primary angle closure glaucoma
Author Affiliations & Notes
  • Mohamad El Wardani
    Glaucoma, Jules Gonin Eye hospital, Lausanne, Switzerland
  • Farid Achache
    Glaucoma, Jules Gonin Eye hospital, Lausanne, Switzerland
  • Ciara Bergin
    Glaucoma, Jules Gonin Eye hospital, Lausanne, Switzerland
  • Kenza Bradly
    Glaucoma, Jules Gonin Eye hospital, Lausanne, Switzerland
  • Eamon Sharkawi
    Glaucoma, Jules Gonin Eye hospital, Lausanne, Switzerland
  • Footnotes
    Commercial Relationships Mohamad El Wardani, None; Farid Achache, None; Ciara Bergin, None; Kenza Bradly, None; Eamon Sharkawi, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 2695. doi:
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      Mohamad El Wardani, Farid Achache, Ciara Bergin, Kenza Bradly, Eamon Sharkawi; Istent implantation combined with phacoemulsification compared to phacoemulsification alone in primary angle closure and primary angle closure glaucoma. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):2695.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose
 

To study the safety and efficacy of combined Istent implantation and phacoemulsification compared to phacoemulsification alone in primary angle closure or primary angle closure glaucoma.

 
Methods
 

A consecutive comparative study of 106 eyes with primary angle closure with ocular hypertension or glaucoma, underwent phacoemulsification alone (n=53 group I) or combined with surgical implantation of one or two Istents (n=53, group II). Preoperatively, all patients had a mean angle size of 0-20° on gonioscopy and required glaucoma medications. Pre and post-operative measures recorded included patient demographics, visual acuity, IOP, number of glaucoma medications and any complications. Patients were assessed preoperatively and on postoperative weeks 1, 3 and months 6 and 12

 
Results
 

Postoperatively at 6 months, mean IOP decreased from 16.8 mmHg to 14.2 mmHg in group I, from 16.7 mmHg to 14.1 mmHg in group II. Mean glaucoma medication decreased from 1.9 to 1.8 in group I, from 2.3 to 1.2 in group II (p<0.05). There were no cases of Istent blockage. No major per- or postoperative complications were recorded in either groups.

 
Conclusions
 

Istent implantation combined with phacoemulsification was uncomplicated in eyes with narrow angles. Combined surgery resulted in similar IOP reduction to phacoemulfication alone, but achieved a significantly greater reduction in glaucoma medications. This may have positive implications for compliance, quality of life and health care costs in angle closure patients.

 
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