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Carl G O Glittenberg, Susanne Binder; Visualization Quality Enhancement of Three Dimensional Swept Source Optical Coherence Tomography Data. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):2768.
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© ARVO (1962-2015); The Authors (2016-present)
To develop algorithms and visualization methods to improve the display quality of swept source optical coherence tomography (SSOCT) data sets.<br />
12mm x 9mm SSOCT scans of diverse vitreo-retinal pathologies of 40 patients were collected using a Topcon™ Atlantis® DRI SSOCT instrument. Additional dense 3D SSOCT scans were collected of the anterior chamber of several patients. The data was exported into Adobe™ After Effects™ and a temporal sampled noise reduction averaging was performed using the Neat Video™ plugin. The resulting data was exported into Maxon™ Cinema 4D™ , where it was displayed as a ray-traced shaded volumetric model with real time interactivity using a custom designed volumetric visualization plugin. Additionally, the data was segmented into threshold based color coded triangle meshes and rendered out on a CUDA capable GPU.<br />
76 eyes of 48 patients were collected. The applied noise reduction greatly improved the visibility of subtle structures in the vitreous as well as resulted in a clearer delineation of the retinal layers. The volumetric visualization using ray-traced shading greatly improved the clarity of subtle three-dimensional structures in the anterior chamber as well as the intra-retinal and epi-retinal space. The segmentation system successfully interpreted and displayed folded and looped structures.<br />
The designed software greatly increases the quality of display of SSOCT data sets. The noise reduction and volumetric display will in the future have great applicability in a clinical setting. The triangle-mesh segmentation has good potential to be used in fluid dynamic and surgical simulation.<br />
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