June 2015
Volume 56, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2015
En-Face Imaging of Microcysts in Macular Teleangiectasia Type 2 Using Minimum- and Mean-Intensity Projections
Author Affiliations & Notes
  • Paul F Stetson
    Carl Zeiss Meditec, Dublin, CA
  • John Legarreta
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL
  • Andrew Dominic Legarreta
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL
  • Mariana R Thorell
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL
  • Giovanni Gregori
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL
  • Philip J Rosenfeld
    Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL
  • Footnotes
    Commercial Relationships Paul Stetson, Carl Zeiss Meditec (E), Carl Zeiss Meditec (P); John Legarreta, Carl Zeiss Meditec (F); Andrew Legarreta, Carl Zeiss Meditec (F); Mariana Thorell, None; Giovanni Gregori, Carl Zeiss Meditec (F); Philip Rosenfeld, Acucela (C), Advanced Cell Technology (F), Alexion Pharmaceuticals (F), Bayer Healthcare Pharmaceuticals (C), Boehringer Ingelheim (C), Carl Zeiss Meditec (F), Chengdu Kanghong Biotech (C), GlaxoSmithKline (F), Oraya (C), Sanofi/ Genzyme (C), ThromboGenics (C)
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 2803. doi:
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      Paul F Stetson, John Legarreta, Andrew Dominic Legarreta, Mariana R Thorell, Giovanni Gregori, Philip J Rosenfeld; En-Face Imaging of Microcysts in Macular Teleangiectasia Type 2 Using Minimum- and Mean-Intensity Projections. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):2803.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose
 

This study is to demonstrate visualization of microcysts in cases of macular teleangiectasia type 2 (MacTel2) using en-face imaging, and to compare minimum-intensity projection with typical mean-intensity projection en-face imaging for the detection of these microcysts.

 
Methods
 

Data from patients with MacTel2 were gathered from a prototype swept-source OCT system. These image volumes were processed offline to create two types of en-face images, one using the mean intensity between the ILM and RPE segmentations, and another using the minimum intensity of the speckle-reduced image between the ILM and RPE segmentations. Apparent microcysts in the en-face images were verified by viewing the B-scans through those locations.

 
Results
 

Microcysts were found in 10 out of 35 eyes using standard mean-intensity projections and 15 out of 35 eyes using minimum-intensity projections.

 
Conclusions
 

Microcysts are commonly found in cases of MacTel2. The minimum-intensity projection allows better detection of these microcysts than standard en-face imaging.  

 
Comparison of minimum- and mean-intensity projections for en-face imaging of microcysts (example indicated in red circle).
 
Comparison of minimum- and mean-intensity projections for en-face imaging of microcysts (example indicated in red circle).

 
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