June 2015
Volume 56, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2015
Alteration in mechanical properties of the lens capsule after cataract surgery
Author Affiliations & Notes
  • Hiroyuki Matsushima
    Ophthalmology, Dokkyo Medical University, Shimotsuga-Gun, Japan
  • Yoko Katsuki
    Ophthalmology, Dokkyo Medical University, Shimotsuga-Gun, Japan
  • Koichiro Mukai
    Ophthalmology, Dokkyo Medical University, Shimotsuga-Gun, Japan
  • Wataru Terauchi
    Ophthalmology, Dokkyo Medical University, Shimotsuga-Gun, Japan
  • Tadashi Senoo
    Ophthalmology, Dokkyo Medical University, Shimotsuga-Gun, Japan
  • Footnotes
    Commercial Relationships Hiroyuki Matsushima, None; Yoko Katsuki, None; Koichiro Mukai, None; Wataru Terauchi, None; Tadashi Senoo, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 2966. doi:
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    • Get Citation

      Hiroyuki Matsushima, Yoko Katsuki, Koichiro Mukai, Wataru Terauchi, Tadashi Senoo; Alteration in mechanical properties of the lens capsule after cataract surgery. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):2966.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose
 

To evaluate mechanical properties changes in the rabbit posterior lens capsule over the postoperative course of cataract surgery.

 
Methods
 

Phacoemulsification was performed for 9-week-old Japanese white rabbits. A capsule tension ring (CTR) and an intraocular lens (IOL: YA-60BB, HOYA) were implanted in the eye (n=3). The lens capsule was extracted in the 4-week postoperative and was fixed by fixture that was placed in normal saline at room temperature. The tensile tester (MINI44, INSTRON) with a rod was used to pierce for measuring the posterior capsule load and displacement to breaking point under the following condition; Gauge Length (1.5 mm), Speed (10 mm/min). The integral load from 1.5 mm to the breaking point in displacement was defined as total deformation energy. For comparison, five capsules, which were extracted immediately after CTR-insertion surgery, were used.

 
Results
 

The results of the piercing-load measurement are shown for the control group (Fig. 1) and the 4-week postoperative group (Fig.2). For total deformation energy, the control group scored 0.038 Nmm, whereas the 4-week postoperative group scored 0.066 Nmm, significantly higher than the control group (P=0.025).

 
Conclusions
 

The lens capsule needs more energy for deformation over the postoperative course of cataract surgery.  

 

 
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