June 2015
Volume 56, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2015
Defocus curve testing of pseudophakic patients: simulations and clinical outcomes.
Author Affiliations & Notes
  • Henk A Weeber
    Abbott Medical Optics, Groningen, Netherlands
  • Carmen Canovas
    Abbott Medical Optics, Groningen, Netherlands
  • Stan Bentow
    Abbott Medical Optics, Santa Ana, CA
  • Sanjeev Kasthurirangan
    Abbott Medical Optics, Santa Ana, CA
  • Eugenia Thomas
    Abbott Medical Optics, Santa Ana, CA
  • Silvestre Manzanera
    Laboratorio de Optica, Universidad de Murcia, Murcia, Spain
  • Pablo Artal
    Laboratorio de Optica, Universidad de Murcia, Murcia, Spain
  • Patricia A Piers
    Abbott Medical Optics, Groningen, Netherlands
  • Footnotes
    Commercial Relationships Henk Weeber, Abbott Medical Opticss (E); Carmen Canovas, Abbott Medical Optics (E); Stan Bentow, Abbott Medical Optics (E); Sanjeev Kasthurirangan, Abbott Medical Optics (E); Eugenia Thomas, Abbott Medical Optics (E); Silvestre Manzanera, Abbott Medical Optics (F); Pablo Artal, Abbott Medical Optics (C), Abbott Medical Optics (F); Patricia Piers, Abbott Medical Optics (E)
  • Footnotes
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Investigative Ophthalmology & Visual Science June 2015, Vol.56, 2985. doi:
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      Henk A Weeber, Carmen Canovas, Stan Bentow, Sanjeev Kasthurirangan, Eugenia Thomas, Silvestre Manzanera, Pablo Artal, Patricia A Piers; Defocus curve testing of pseudophakic patients: simulations and clinical outcomes.. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):2985.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To compare different methodologies to predict defocus curves of pseudophakic patients, and to compare these predictions with clinically-obtained defocus curves.

Methods: The through-focus performance of the pseudophakic eye was evaluated in laboratory and clinical settings. Measurements included computer-simulated defocus curves, through-focus image quality testing on an optical bench, and defocus curves obtained for subjects using an adaptive optics vision simulator (AOVS). The results were compared to available clinically obtained defocus curves of two intraocular lens designs.

Results: Predicted visual acuity at distance was better than 0.0 logMAR for the two methods that determined visual acuity (simulations, AOVS). This corresponded with the clinical results. For eyes implanted with an extended range of vision IOL, the simulations and AOVS predicted the clinically‑obtained defocus curve within 0.1 logMAR up to and including ‑2.0 diopters of defocus. For higher values of defocus, the simulations overestimated the clinically obtained visual acuity, and the AOVS slightly underestimated the clinically obtained visual acuity. Correlation of the image quality on the optical bench and the clinically‑obtained defocus curves varied, depending on the spatial frequency evaluated.

Conclusions: Simulation of defocus curves and measurements using an AOVS correspond well with clinically‑obtained defocus curves. Prediction of defocus curves using through-focus image quality measured on an optical bench depends on the spatial frequency content evaluated.

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