Purchase this article with an account.
Laura Andrea Torrado, Juan Carlos Serna-Ojeda, Enrique Ariza-Camacho, Alberto Collado- Solorzano, Blanca C Flores- Sanchez, Abelardo Rodriguez- Reyes, Emiliano Fulda-Graue; Adenoma of the nonpigmented ciliary body and iris epithelium in Mexican mestizo patients. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):3408.
Download citation file:
© ARVO (1962-2015); The Authors (2016-present)
Describe the clinical characteristics, ultrasound findings, and histopathologic and immunohistochemical results from mexican mestizo patients with adenoma of the nonpigmented ciliary body and iris epithelium
Retrospective analysis of the interventional case series of four patients with final diagnosis of adenoma of the nonpigmented ciliary body and iris epithelium.
Median age at presentation was 50 years (range 15 - 75 years). Half of the patients presented with decreased visual acuity and the other half with changes in iris pigmentation. Ultrasound revealed a solid mass of homogeneous density and high internal reflectivity and the biomicroscopy showed the anatomical origin. In all the patients an excisional biopsy with partial lamellar sclerouvectomy was performed for accurate diagnosis. One patient required a 23-gauge vitrectomy at the same surgical time because of retinal detachment. Histopathology reported sheets of cells with clear cytoplasm surrounded by basement membrane and tubular differentiation. Inmunohitochemistry was positive por vimentin, S-100, epithelial membrane antigen (EMA) and neuron specific enolase (NSE).
The adenoma of the nonpigmented ciliary body is a benign rare tumor with few reports in literature, being this the first latin american case series of this entity. Because of its origin, the clinical presentation is varied without an established pattern and it may be confused with other tumors, thus in order to make the diagnosis of this adenoma, resection is needed along with histopathologic analysis and the identification of specific immunohistochemical markers.
This PDF is available to Subscribers Only