June 2015
Volume 56, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2015
Thickness maps of the macular intra retinal layers and the choroid using optical coherence tomography in myopic eyes
Author Affiliations & Notes
  • Ye Yang
    Special Examination Centre, Eye Hospital, Wenzhou, China
  • Meixiao Shen
    Special Examination Centre, Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou, China
  • Jianhua Wang
    Bascom Palmer Eye Inst Lib, Miami, FL
  • Shenghai Huang
    Special Examination Centre, Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou, China
  • Footnotes
    Commercial Relationships Ye Yang, None; Meixiao Shen, None; Jianhua Wang, None; Shenghai Huang, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 3758. doi:
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      Ye Yang, Meixiao Shen, Jianhua Wang, Shenghai Huang; Thickness maps of the macular intra retinal layers and the choroid using optical coherence tomography in myopic eyes. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):3758.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose
 

To examine and compare the retinal thickness (RT) and choroid thickness (ChT) and their topographic variations across the posterior pole in high myopia and low myopia persons

 
Methods
 

A total of 25 subjectshad retinal and choroid measured using RTVue-100 optical coherence tomography (OCT). Fifteen of them had high myopia aged 16 to 39 years (mean age,27.94±1.13 years,SE: -9.50±2.00 diopters [D]), ten of them had low myopic aged from 18 to 36 years (mean age, 26.61±1.11,SE: -1.50±1.00 diopters [D]). Twelve radial OCT line scans centered on the fovea were assessed for each person. RT and CHT were delineated of nine macular sectors, according to the EDTRS by automated segmentation algorithm developed at the Wenzhou Medical University. Eight intra-retinal layers were semi-automatically segmented, including RNFL, GCL-IPL, INL, OPL,ONL, IS, OS, RPE layer.

 
Results
 

ChT was significantly thinner in high myopes compared to low myopes[j1] in all nine sectors. GCL-IPL was thinner in myopes in superior (1.5~3.0mm), temporal(1.5~3.0mm), inferior (1.5~3.0mm), nasal(1.5~3.0mm), RNFL was thinner in myopes in superior (1.5~3.0mm), temporal(1.5~3.0mm), inferior (1.5~3.0mm), INL was thinner in myopes in temporal (1.5~3.0mm), inferior (1.5~3.0mm), nasal (1.5~3.0mm), OPL had no difference in all the nine sectors between high myopes and low myopes, ONL was thinner in myopes in central foveal regions, superior(0.5~1.5mm), temporal (0.5~1.5mm), superior (1.5~3.0mm), temporal (1.5~3.0mm), inferior (1.5~3.0mm), IS layer was thicker in superior (0.5~1.5mm) and superior (1.5~3.0mm), OS layer was thicker in superior (1.5~3.0mm) and temporal (1.5~3.0mm), RPE layer was thicker in superior (0.5~3.0mm).

 
Conclusions
 

High myopic persons have significantly thinner choroids compared to low myopic persons of similar age, particularly in central foveal regions. GCL-IPL, RNFL,INL were thinner in some region, especially outer region in myopia persons, and OPL had no difference in statistic in all the nine sectors between the high myopes and low myopes, OS, IS and RPE layers were thicker in some regions in high myopia persons.  

 
Figure1: Eight intra-retinal layers and choroid map.RNL:retinal nerve fiber layer;GCL-IPL:ganglion cell layer-inner plexiform layer;INL:inner nuclear layer;OPL:outer plexiform layer;ONL:outer nuclear layer;IS:inner segment;OS:outer segment;RPE:retinal pigmentosa epithelium.<br /> <br />
 
Figure1: Eight intra-retinal layers and choroid map.RNL:retinal nerve fiber layer;GCL-IPL:ganglion cell layer-inner plexiform layer;INL:inner nuclear layer;OPL:outer plexiform layer;ONL:outer nuclear layer;IS:inner segment;OS:outer segment;RPE:retinal pigmentosa epithelium.<br /> <br />
 

 
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