June 2015
Volume 56, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2015
Foveal Detachment after Idiopathic Macular Hole Treatment
Author Affiliations & Notes
  • Aude Couturier
    ophtalmologie, Hopital Lariboisiere, AP-HP, Université Paris 7 - Sorbonne Paris Cité, Paris, France
  • Elise Boulanger-Semama
    ophtalmologie, Hopital Lariboisiere, AP-HP, Université Paris 7 - Sorbonne Paris Cité, Paris, France
  • Rabih Hage
    ophtalmologie, Hopital Lariboisiere, AP-HP, Université Paris 7 - Sorbonne Paris Cité, Paris, France
  • Pascale G Massin
    ophtalmologie, Hopital Lariboisiere, AP-HP, Université Paris 7 - Sorbonne Paris Cité, Paris, France
  • Alain Gaudric
    ophtalmologie, Hopital Lariboisiere, AP-HP, Université Paris 7 - Sorbonne Paris Cité, Paris, France
  • Ramin Tadayoni
    ophtalmologie, Hopital Lariboisiere, AP-HP, Université Paris 7 - Sorbonne Paris Cité, Paris, France
  • Footnotes
    Commercial Relationships Aude Couturier, None; Elise Boulanger-Semama, None; Rabih Hage, None; Pascale Massin, None; Alain Gaudric, None; Ramin Tadayoni, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 5083. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to Subscribers Only
      Sign In or Create an Account ×
    • Get Citation

      Aude Couturier, Elise Boulanger-Semama, Rabih Hage, Pascale G Massin, Alain Gaudric, Ramin Tadayoni; Foveal Detachment after Idiopathic Macular Hole Treatment. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):5083.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract
 
Purpose
 

To analyze the foveal microstructure of eyes treated for idiopathic macular hole (MH) and to identify clinical and anatomical risk factors of post treatment foveal detachment (FD).

 
Methods
 

A retrospective analysis was performed on 105 eyes from 105 consecutive patients treated for MH. This included 100 eyes treated by vitrectomy and gas tamponade and 5 eyes treated by a single intravitreal injection of ocriplasmin. The anatomical features of FD detected on postoperative spectral-domain optical coherence tomography (SD-OCT) were analyzed and correlated with morphological and clinical data at baseline, 1 month and 3 months after treatment. The size of defect was measured and compared with pre-treatment MH base diameter.

 
Results
 

In the 100 eyes treated surgically, FD were noted on postoperative SD-OCT in 18% of eyes (12/65 eyes) and 4% (3/70 eyes) at 1 months and 3 months after surgery respectively. The base diameter of the defect at 1 month (371±92 μm) and 3 months (341±104 μm) postoperatively was always smaller than the preoperative MH base diameter (766±203 μm). Conversely, in the eyes treated by ocriplasmin, FD was noted in all eyes and the base diameter of the defect at 1 month (1375± 842 μm) and 3 months (903±833 μm) after the injection was always larger than the preoperative MH base diameter (544±61 μm). FD did not significantly alter visual recovery in closed MH surgically. FD did not statistically decrease the visual acuity in eyes treated with ocriplasmin (from 0.7 to 0.68 Logmar before and 1 month after the injection respectively).

 
Conclusions
 

This is the first SD-OCT study of foveal anatomy in FD after MH surgical and non-surgical treatment. The base diameter of FD was always smaller than the preoperative MH base diameter after vitrectomy. Conversely, the base diameter of FD was always larger after intravitreal ocriplasmin suggesting a specific effect of this enzyme.  

 
Figure: A and B. SD-OCT of a macular hole (MH) treated surgically. A. The MH preoperative base diameter was measured at 478 μm. B. The postoperative SD-OCT showed a foveal detachment with a base diameter of 256 μm, 1 month after surgery. C and D. SD-OCT of a MH treated with an intravitreal injection of ocriplasmin. C. The initial base diameter of the MH was measured at 501 μm. D. A foveal detachment was detected on SD-OCT 1 month after the injection and the base diameter of the defect was measured at 2202 μm.
 
Figure: A and B. SD-OCT of a macular hole (MH) treated surgically. A. The MH preoperative base diameter was measured at 478 μm. B. The postoperative SD-OCT showed a foveal detachment with a base diameter of 256 μm, 1 month after surgery. C and D. SD-OCT of a MH treated with an intravitreal injection of ocriplasmin. C. The initial base diameter of the MH was measured at 501 μm. D. A foveal detachment was detected on SD-OCT 1 month after the injection and the base diameter of the defect was measured at 2202 μm.

 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×