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Paulina Nunez, Juan Carlos Serna-Ojeda, Alberto Abdala Figuerola, Osiris Olvera Morales; Thyroid-associated ophthalmopathy: Epidemiologic characteristics in a reference institution in Mexico City.. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):568.
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Describe the epidemiological characteristics in Mexican population with thyroid-associated ophthalmopathy and a comparison with other series reported in literature.<br />
A descriptive, retrospective and observational study was performed in the Thyroid Clinic of the Department of oculoplastic and orbital surgery in a reference institution through the revision of clinical records. Patients of any age and gender with confirmed diagnosis of thyroid-associated orbitopathy were included. We excluded patients with high myopia and other causes of proptosis, incomplete files, or patients with a history of any ocular surgery related to thyroid eye disease. The variables included in the study were sex, age, smoking history, thyroid status, exophthalmometry and presence of clinical signs like eyelid retraction at the time of first consultation through a thyroid profile. A descriptive investigation was performed for the variables according to its distribution and the intergroup analysis was done with Student's t test.<br />
A total of 241 patients, 187 (77.6%) females and 54 (22.4%) males were included. The 40 to 59 years interval was the predominant group (56.4%) for the presentation of the disease. In relation to smoking history, 42.3% of patients reported a positive history for smoking. The thyroid status that predominated at the time of diagnosis of thyroid-associated ophthalmopathy was euthyroidism with 47.3%. The exophthalmometry had a media of 19.8mm. The most common clinical sign was eyelid retraction in 83.4% of the patients.
Variables such as age, sex and eyelid retraction presented in similar proportions to those reported in studies conducted in different countries and ethnic groups. In Mexican population the initial thyroid hormone status is variable and patients may present with eye manifestations despite of having a profile in normal ranges.<br />
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