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Santiago Delgado-Tirado, Yazmin Báez-Peralta, Lucia Gonzalez-Buendia, Iztiar Fernandez, Miguel José Maldonado, Rosa Coco; WAVEFRONT ANALYSIS OF HIGHER-ORDER ABERRATIONS IN PATIENTS WITH HIGH MYOPIA. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):6017.
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We performed a prospective, observational and analytical study to elucidate the correlation between axial length (AXL) and higher-order aberrations (HOAs) in patients with high myopia (<-6D). It is believed that an increase in HOAs is correlated with a significant decrease in quality of vision, especially under scotopic conditions.
We analysed 95 eyes from 51 high myopic patients, with a median age of 43 years. Patients presenting any corneal or lens disease that could interfere in their aberrometry values, and those suffering any macular disease evidenced by OCT (3D OCT-2000 FA plus, Topcon) were excluded. Wavefront analysis of corneal, internal and ocular aberrations was performed with a Hartmann-Shack aberrometer (Wavefront® Analyzer KR-1W, Topcon). In order to assess the relationship between both variables the Spearman correlation coefficient was used.
A statistically significant positive correlation between AXL and internal spherical aberration was detected for the whole sample. Besides, a statistically significant positive correlation between AXL and internal tetrafoil aberration, was observed.
According to our results, patients with high myopia show greater values of HOAs. Thus, it appears to be a positive correlation between AXL and internal aberrometry. This findings may help to understand why patients with high myopia reiteratedly complain about its poor quality of vision, despite of having an optimum correction of their refractive error and a good visual acuity.
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