June 2015
Volume 56, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2015
Efficacy of Pneumatic Trabeculoplasty in Ocular Hypertension and primary open angle glaucoma and anatomical impact evaluated by ultrasound biomicroscopy
Author Affiliations & Notes
  • Olivier Lichtwitz
    Ophthalmology, University Hospital Poitiers, Bordeaux, France
  • Martial Mercié
    Ophthalmology, University Hospital Poitiers, Bordeaux, France
  • Michèle Boissonnot
    Ophthalmology, University Hospital Poitiers, Bordeaux, France
  • Nicolas Leveziel
    Ophthalmology, University Hospital Poitiers, Bordeaux, France
  • Footnotes
    Commercial Relationships Olivier Lichtwitz, None; Martial Mercié, None; Michèle Boissonnot, None; Nicolas Leveziel, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 6130. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to Subscribers Only
      Sign In or Create an Account ×
    • Get Citation

      Olivier Lichtwitz, Martial Mercié, Michèle Boissonnot, Nicolas Leveziel; Efficacy of Pneumatic Trabeculoplasty in Ocular Hypertension and primary open angle glaucoma and anatomical impact evaluated by ultrasound biomicroscopy. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):6130.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract
 
Purpose
 

Pneumatic Trabeculoplasty (PNT) is a novel technique that reduces intraocular pressure (IOP). To evaluate the efficacy and the safety of PNT in patients with ocular hypertension (OHT) or ocular primary open angle glaucoma (POAG). To analyse the ocular anatomical changes using ultrasound biomicroscopy (UBM).

 
Methods
 

23 eyes of 23 patients with OHT or POAG and IOP > 21 mmHg were enrolled in this prospective study with a follow-up of 6 months. At baseline and at 6 months patients underwent BCVA, biomicroscopy, daytime IOP curve, gonioscopy, visual field 24-2, optic nerve SD-OCT and UBM examination. One eye was included in this study while the fellow eye was used as intra-individual control. A single PNT treatment included a combination of a vacuum application for 60 seconds followed by a 5 minutes rest period and by another PNT application. All patients underwent a single PNT at day 0 (baseline), 7, 90 and 180. The degree of opening of the anterior chamber angle and the surface of the ciliary body were recorded. Patient was considered responder if IOP reduction > 15% baseline IOP.

 
Results
 

At baseline, median IOP was 26.1 ± 1.9 mmHg in the treated eye, and 22.2 ± 2.2 mmHg in the fellow eye. 19 eyes (82.6%) were responders to PNT on day 90 and 180. At 6 months mean IOP was 21.4 ± 3.2 mmHg (-4.7 mmHg) in the treated eye. At 6 months, for good responders, median IOP was finally of 20.6 ± 1,7 mmHg with a median IOP decrease of 5.5 mmHg. Eyes responders to PNT showed a significant reduction of ciliary body area (mean decrease of 7.4 ± 3.5%, p<0.0001) compared to the fellow eyes (0.7 ± 1.6%, p=0.09), whereas non responders to PNT didn’t shown statistically significant reduction of ciliary body area compared to fellow eyes (p=0.07).

 
Conclusions
 

Our experience showed a mean IOP reduction of 4.7 mmHg from the baseline after 180 days in the treated eye by PNT. UBM analysis seems to confirm a cyclo-suppression effect with a likely decline in production of aqueous humor by the ciliary body.  

 
Suction ring of ​pneumatic trabeculoplasty
 
Suction ring of ​pneumatic trabeculoplasty
 
 
Ciliary body by ultrasound biomicroscopy
 
Ciliary body by ultrasound biomicroscopy

 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×