June 2015
Volume 56, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2015
Clinical implications of the changes in macular sensitivity and foveal thickness after phacoemulsification in cataract patients with diabetes
Author Affiliations & Notes
  • Lei Cai
    EYE & ENT Hospital of Fudan University, Shanghai, China
  • Jin Yang
    EYE & ENT Hospital of Fudan University, Shanghai, China
  • zhongcui sun
    EYE & ENT Hospital of Fudan University, Shanghai, China
  • Hongfei Ye
    EYE & ENT Hospital of Fudan University, Shanghai, China
  • Yi Lu
    EYE & ENT Hospital of Fudan University, Shanghai, China
  • Footnotes
    Commercial Relationships Lei Cai, None; Jin Yang, None; zhongcui sun, None; Hongfei Ye, None; Yi Lu, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 673. doi:
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      Lei Cai, Jin Yang, zhongcui sun, Hongfei Ye, Yi Lu, ; Clinical implications of the changes in macular sensitivity and foveal thickness after phacoemulsification in cataract patients with diabetes. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):673.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose
 

To investigate the changes in Optical coherence tomography (OCT), microperimetry (MP), and visual acuity (VA) of a large series of diabetic patients after phacoemulsification and to evaluate its clinical implications.

 
Methods
 

A total of 1002 cataract patients with diabetes mellitus (DM) were recruited. OCT and microperimetry testing were performed within 4 weeks before surgery and at postoperative week 1, and month 1, 3. Best-corrected visual acuity (BCVA) in Log MAR was recorded. Pseudophakic cystoid macular edema (PCME) was defined as an increase of center point thickness on OCT 30% from preoperative baseline, as well as a decrease (≥2dB) of the macular sensitivity (MS).

 
Results
 

1002 eyes completed 3-month follow-up, of which 521 participants (521 eyes) had a diabetes mellitus (DM) duration of ≥ 5 years, while 481 participants (481 eyes) had a DM duration of less than 5 years. Based on the diagnosis standard (an increase in FT by 30%), 47 patients were diagnosed as PCME (an incidence of 4.69%). Of the 47 PCME patients, 38 patients had a DM duration of ≥ 5 years, a contrast to 9 patients who had a DM duration of less than 5 years. The incidence of PCME was significantly greater in patients of ≥ 5 years DM duration than in patients of < 5years DM duration (odds ratio [OR] = 4.5821, 95% CI, 2.2394 - 9.3755; p = 0.022[ZZ1] ) In the PCME patients, FT is significantly thicker at 1-month follow-up than that at 1-week follow-up, and MS is significantly lower at postoperative 1 month than that at postoperative 1 week, both of which returned to the 1-week levels by 3 months. Of the 47 PCME patients, 20 patients were simultaneously with a decrease of MS (≥2dB) (OCT plus MP examination) while 8 patients had a decrease of BCVA (≥ 2 lines) (OCT plus BCVA). A significant difference was found between the two methods designed for evaluating the macular function.

 
Conclusions
 

Individuals with a long duration of diabetes are predisposed to PCME after uneventful phacoemulsification; the combination of OCT and MS can act as an effective method to evaluate the macular function after phacoemulsification for the cataract patients with diabetes.  

 
The changes in FT in PCME patients (detected by OCT plus MS) at all visits
 
The changes in FT in PCME patients (detected by OCT plus MS) at all visits
 
 
The changes in MS in PCME patients (detected by OCT plus MS) at all visits
 
The changes in MS in PCME patients (detected by OCT plus MS) at all visits

 
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