June 2015
Volume 56, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2015
ANATOMIC PREDICTORS OF INTRAOCULAR PRESSURE LOWERING POST PHACOEMUSIFICATION: AN ASOCT STUDY
Author Affiliations & Notes
  • norlina ramli
    Ophthalmology, University of Malaya Eye Research Centre, Kuala Lumpur, Malaysia
  • Li Yen Chan
    Ophthalmology, University of Malaya Eye Research Centre, Kuala Lumpur, Malaysia
  • Amir Samsudin
    Ophthalmology, University of Malaya Eye Research Centre, Kuala Lumpur, Malaysia
  • mohammadreza peyman
    Ophthalmology, University of Malaya Eye Research Centre, Kuala Lumpur, Malaysia
  • Monisha Esther Nongpiur
    Singapore National eye Centre, Singapore Eye Research Institute, Singapore, Singapore
  • Mingguang He
    Sun Yat Sen University, Key Laboratory of Ophthalmology, Zhongshan Ophthalmic centre, Guangzhou, China
  • mimiwati zahari
    Ophthalmology, University of Malaya Eye Research Centre, Kuala Lumpur, Malaysia
  • Footnotes
    Commercial Relationships norlina ramli, None; Li Yen Chan, None; Amir Samsudin, None; mohammadreza peyman, None; Monisha Nongpiur, None; Mingguang He, None; mimiwati zahari, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 680. doi:
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      norlina ramli, Li Yen Chan, Amir Samsudin, mohammadreza peyman, Monisha Esther Nongpiur, Mingguang He, mimiwati zahari; ANATOMIC PREDICTORS OF INTRAOCULAR PRESSURE LOWERING POST PHACOEMUSIFICATION: AN ASOCT STUDY. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):680.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To investigate anterior segment parameters and biometric factors associated with intraocular pressure (IOP) lowering after uneventful phacoemulsification

Methods: This prospective, single centre study conducted in University Malaya Medical Centre, Kuala Lumpur between July, 2013 and February, 2014. All participants underwent uneventful phacoemulsification with foldable intraocular lens implantation. Only the right eye was used for analysis if both eyes were eligible. IOP measurement, gonioscopy and anterior segment optical coherence tomography (ASOCT; Carl Zeiss, Meditec, Dublin, CA) measurements were performed preoperatively and postoperatively at 1 week and 1 month. Customised software (Zhongshan Angle Assesment Programme -ZAAP) was used to measure various anterior chamber parameters including central corneal thickness (CCT), anterior chamber depth (ACD), anterior chamber width (ACW), angle opening distance at 500 microns(AOD 500) anterior to the scleral spur and lens vault (LV). A-scan biometry (US800, Nidek Co Ltd, Tokyo, Japan) was used to measure axial length (AL) and lens thickness (LT) and and calculate lens position(LP) and relative lens position (RLP). Univariate and multivariate analysis were performed to determine the predictive factors of IOP lowering after phacoemulsification.

Results: Eighty-six eyes from 86 patients were included in the study. The mean IOP reduced significantly (16.24 ± 2.4 mmHg to 14.1 ± 2.6 mmHg at 1 week and 14.4 ± 2.3 mmHg at 1 month) (p < 0.001 for both) after phacoemulsification. The AOD500 increased significantly (0.46 ± 0.25 mm to 0.69 ± 0.17 mm at 1 week and 0.72 ± 0.18 mm at 1 month) after surgery(p<0.001 for both). Anterior chamber depth increased significantly (2.89 ± 0.3 mm to 4.05 ± 0.35 mm at i week and 4.11 ± 0.30 mm) also (p<0.001). Reduction in IOP correlated with the increase in AOD500 (r = 0.24, p = 0.035) at 1 month after surgery. In the multiple regression model, axial length was the only factor which correlated with percentage change in IOP (standardised beta=0.232, p=0.01) after adjusting for age and CCT.

Conclusions: This hospital based study shows that a higher axial length is independent predictor of intraocular pressure lowering post uncomplicated phacoemusification.

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