June 2015
Volume 56, Issue 7
Free
ARVO Annual Meeting Abstract  |   June 2015
Short-term Effects of Combined Extremely Low Frequency Pulsed Electromagnetic Field and Pulsed Low Level Laser Therapy on Rabbit Model of Corneal Alkaline Burn
Author Affiliations & Notes
  • Mozhgan Rezaeikanavi
    Ophthalmic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran (the Islamic Republic of)
    Ocular Tissue Engineering Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran (the Islamic Republic of)
  • Faraj Tabeie
    Department of Basic Sciences, Faculty of Rehabilitation Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran (the Islamic Republic of)
  • Farzin Sahebjam
    Ocular Tissue Engineering Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran (the Islamic Republic of)
  • Nima Poursani
    Ocular Tissue Engineering Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran (the Islamic Republic of)
  • Nazanin Jahanbakhsh
    Ocular Tissue Engineering Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran (the Islamic Republic of)
  • Pouya Paymanpour
    Ocular Tissue Engineering Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran (the Islamic Republic of)
  • Sasha AfsarAski
    Ocular Tissue Engineering Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran (the Islamic Republic of)
  • Footnotes
    Commercial Relationships Mozhgan Rezaeikanavi, None; Faraj Tabeie, None; Farzin Sahebjam, None; Nima Poursani, None; Nazanin Jahanbakhsh, None; Pouya Paymanpour, None; Sasha AfsarAski, None
  • Footnotes
    Support None
Investigative Ophthalmology & Visual Science June 2015, Vol.56, 733. doi:
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      Mozhgan Rezaeikanavi, Faraj Tabeie, Farzin Sahebjam, Nima Poursani, Nazanin Jahanbakhsh, Pouya Paymanpour, Sasha AfsarAski; Short-term Effects of Combined Extremely Low Frequency Pulsed Electromagnetic Field and Pulsed Low Level Laser Therapy on Rabbit Model of Corneal Alkaline Burn. Invest. Ophthalmol. Vis. Sci. 2015;56(7 ):733.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: To investigate the effect of combination of extremely low frequency pulsed magnetic field (ELF-PEMF) and low level laser therapy (LLLT) on alkaline-burnt cornea in rabbits.

Methods: Fifty alkaline-burned corneas from 50 rabbits were categorized into five groups: ELF-PEMF therapy with 2 mTesla intensity (ELF 2) for 30 minutes twice daily, LLLT for 30

Results: No significant difference was noted in area of corneal defect between ELF, LLLT, and ELF+LLLT groups on days 2, 7, and 14. Excluding the controls, rate of significant corneal neovascularization was not statistically different between the groups. The keratocyte loss in MT was significantly higher than in the ELF, LLLT, and ELF+LLLT groups. Moderate to severe inflammation in the LLLT group was comparable with the MT and significantly less than other groups.

Conclusions: Combination of LLLT and ELF2 was not superior to ELF or LLLT alone in healing alkaline-burned corneas. However, given the lower intensity of corneal inflammation as well as lower rate of keratocytes loss with LLLT, it seems that LLLT may be superior to other proposed treatment modalities for alkaline-burnt corneal healing.

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