March 2012
Volume 53, Issue 14
ARVO Annual Meeting Abstract  |   March 2012
A Preliminary Study Of An Active Microvalve For Glaucoma
Author Affiliations & Notes
  • Fabio A. Guarnieri
    Bioengineering, CIMEC (INTEC-CONICET), Santa Fe, Argentina
  • Fernando Sassetti
    Bioengineering, CIMEC (INTEC-CONICET), Santa Fe, Argentina
  • Luciano Garelli
    Bioengineering, CIMEC (INTEC-CONICET), Santa Fe, Argentina
  • Footnotes
    Commercial Relationships  Fabio A. Guarnieri, 20100042209 (P); Fernando Sassetti, None; Luciano Garelli, None
  • Footnotes
    Support  Fundacion Argentina de Nanotecnologia
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 339. doi:
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    • Get Citation

      Fabio A. Guarnieri, Fernando Sassetti, Luciano Garelli; A Preliminary Study Of An Active Microvalve For Glaucoma. Invest. Ophthalmol. Vis. Sci. 2012;53(14):339.

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      © ARVO (1962-2015); The Authors (2016-present)

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Purpose: : In this study, the characterisation of a preliminary design of an active glaucoma drainage device is presented.

Methods: : The valve is actuated by conducting polymers and fabricated by MEMS technology. The characterisation process is performed by numerical simulation using the finite element method and a circuit model, and by in vitro hydrodynamic testing.

Results: : The hydraulic resistance of the designed GDD varies in the range of 13.08-0.36 mmHg min/μl compared with 3.38-0.43 mmHg min/μl for the Ahmed valve. The maximum displacement of the diaphragm in the vertical direction is 18.9 μm, and the strain in the plane is 2%.

Conclusions: : The proposed preliminary design allows to control the IOP by varying the hydraulic resistance in a greater range than the existing passive valves, and the numerical simulation facilitates the characterisation and the improvement of the design before its construction, reducing time and costs.

Keywords: intraocular pressure • clinical laboratory testing • computational modeling 

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