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Won June Lee, Byung Ro Lee, Yong Un Shin, Sam Seo; Fundus Autofluorescence Imaging Patterns In Central Serous Chorioretinopathy According To Chronicity. Invest. Ophthalmol. Vis. Sci. 2012;53(14):933.
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© ARVO (1962-2015); The Authors (2016-present)
To investigate the patterns of fundus autofluorescence (FAF) in central serous chorioretinopathy (CSC) according to chronicity.
Retrospective, observational case series. FAF images from 67 consecutive eyes of 63 patients diagnosed with CSC were retrospectively evaluated and compared with angiographic and spectral-domain optical coherence tomography (SD-OCT) findings. Fluorescein angiography and FAF imaging was performed using an F-10 confocal scanning laser ophthalmoscope (cSLO) (Nidek,Gmagori, Japan).
Acute CSC eyes (18/21 eyes; 85.7%) were characterized by decreased FAF intensity at the leakage point or in the area of serous retinal detachment. In early chronic CSC eyes, increased FAF intensity was seen at the site of serous retinal detachment in 13/17 eyes (76.5%). Eyes with late chronic CSC had irregular FAF image patterns with decreased intensity over areas of RPE atrophy in 26/29 eyes (89.7%). In 15 eyes, discrete granules with increased FAF intensity were observed. In 10 eyes, drainage tracts showed different FAF intensities according to chronicity that corresponded to the RPE status as determined by SD-OCT.
FAF imaging patterns in CSC eyes differ according to the course of the disease, reflecting RPE and outer retinal changes. FAF imaging is therefore a useful noninvasive technique for evaluating the chronicity of CSC.
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