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Sorinela Roata, Belynda Tita, Mounir Drief, Pierre Bonicel; Intravitreal Ranibizumab For Choroidal Neovascularisation In Fundus Flavimaculatus. Invest. Ophthalmol. Vis. Sci. 2012;53(14):943.
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We present a case-based study of late-onset fundus flavimaculatus complicated with choroidal neovascularisation.A treatment with intravitreal ranibizumab was performed.
Our patient, a 65 years old woman, has been previously diagnosed with late onset Stargardt disease upon complete ophtalmologic examination, including IVFA,EOG and multifocal ERG.We documented juxtafoveolar choroidal neovascularisation using IVFA and OCT.A treatment with intravitreal ranibizumab was performed.
We noted the resorbtion of the subretinal fluid and an increase in visual acuity with disparition of metamorphopsias.
Late age of onset has been reported in 20% of Stargardt cases.The lipoproteic scrap deposits could induce alterations of the pigmentary epithelium and Bruch membrane rupture followed by choroidal neovascularisation.This entity has a slower progression and a better visual prognosis. Treatment by intravitreal ranibizumab induced total regression of the choroidal neovascularisation.
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