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Jaeryung Oh, Jong-Hyun Oh, Seong-Woo Kim, Chungkwon Yoo, Kuhl Huh; En-face Imaging With Spectral Domain Optical Coherence Tomography Of The Intraretinal Cystoid Spaces In Type 2 Idiopathic Macular Telangiectasia, Diabetic Macular Edema, And Retinal Vein Occlusion. Invest. Ophthalmol. Vis. Sci. 2012;53(14):948.
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© ARVO (1962-2015); The Authors (2016-present)
To compare the morphologic characteristics of the intraretinal cystoid spaces on en-face images with spectral domain optical coherence tomography (SD-OCT) of eyes with type 2 idiopathic macular telangiectasia (MacTel type 2) with those of diabetic macular edema (DME) and retinal vein occlusion (RVO).
We obtained en-face images of eyes with MacTel type 2, DME, and RVO from SD-OCT database. After processing an en-face image with cystoid spaces into ImageJ, boundary of the cystoid space was determined. Using ImageJ software, the circularity was measured to represent the boundary shape of the cystoid space and the mean gray value was measured to represent the reflectivity. Circularity and mean gray value within the cystoid space were compared between groups. In eyes with MacTel type 2, cystoid spaces of en-face OCT imaging were matched on the fluorescein angiography.
Sixteen eyes with MacTel type 2, 21 with DME, and 20 with RVO were included for analysis. The circularity of the cystoid spaces of MacTel type 2 (mean, 0.491) was lower than those of RVO (0.7333, P<0.001) or DME (0.747, P<0.001). Mean gray value ratio of the cystoid spaces of MacTel type 2 (12.21) and RVO (12.74) was lower than one of DME (20.25, P=0.004, P=0.008). In eyes with MacTel type 2, cystoid spaces were located in foveal center or parafoveal area. All foveolar cystoid spaces did not have a similar location with the angiographic leakage.
En-face imaging with SD-OCT showed topographic characteristics of the cystoid spaces in the eye with MacTel type 2, which was different from those of RVO or DME.
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