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So Hyun Bae, Joonhee Cho, Jae Ryong Han, Woo Ho Nam, Ha Kyoung Kim; Comparative Analysis Of The Distribution Of The Choroidal Thickness In Central Serous Chorioretinopathy On Spectral Domain Optical Coherence Tomography. Invest. Ophthalmol. Vis. Sci. 2012;53(14):972.
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to assess the distribution of choroidal thickness of central serous chorioretinopathy (CSC) using spectral domain optical coherence tomography (SD OCT) in comparison with changes of retinal pigment epithelium (RPE) on fluorescein angiography (FA)
A total of 50 eyes were enrolled including 23 eyes with CSC and 27 normal eyes. Choroidal thickness was measured by Cirrus OCT at 9 points beneath the fovea and at 1 or 2.25mm away from the fovea on superior, nasal, inferior and temporal direction. If the RPE leakage on FA was on the same direction from the fovea with choroidal thickness measurement point, the value of choroidal thickness was categorized as ‘same location’ subgroup and vice versa, ‘opposite location’.
The choroidal thickness in CSC was significantly thicker than that of normal eyes at each measurement point (P<0.01). The subfoveal choroidal thickness was thickest in CSC group. The difference of nasal choroidal thickness between eyes with CSC and normal eyes was greater than those of other measurement points (P<0.01). The choroidal thickness at the ‘same location’ with RPE leakage was significantly thicker than that at the ‘opposite location’ (P<0.01).
The choroidal thickness in CSC was significantly thicker than that of normal eyes. In CSC, the capacity of choroidal expansion differs over the choroid, resulting in greater increment of nasal choroidal thickness. Comparisons between the distribution of choroidal thickness and RPE leakage, revealed that the choroidal thickness was thicker near RPE leakage.
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