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Phoebe Lin, Paul Hahn, Sharon Fekrat; Duchenne Muscular Dystrophy-associated Proliferative Retinal Vasculopathy Successfully Treated With Panretinal Laser Photocoagulation. Invest. Ophthalmol. Vis. Sci. 2012;53(14):977.
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© ARVO (1962-2015); The Authors (2016-present)
To report a case of a patient with Duchenne's muscular dystrophy (DMD) and retinal vasculopathy that regressed with panretinal photocoagulation (PRP).
Retrospective interventional case report.
A 23 year old Caucasian male with advanced DMD presented with a 3 week history of floaters and visual acuity of 20/20 OU. The anterior segment examination was unremarkable without neovascularization. Ophthalmoscopy (Fig.A-B) demonstrated extensive retinal arteriolar aneurysmal dilatations and venous beading OU (Fig. B, inset). Fluorescein angiography (Fig. C-D) highlighted the diffuse aneurysmal dilatations (Fig. C, inset), peripheral capillary non-perfusion (Fig. D, inset), and leaking hyperfluorescence consistent with neovascularization OU. Both eyes were promptly treated with PRP, resulting in regression of neovascularization and resolution of aneurysmal dilatations in both eyes (Fig E-F, insets).
Proliferative retinal vasculopathy from DMD can be successfully treated with PRP preventing the rapid progression of retinopathy that has been previously reported in the literature.
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