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Daniel H. Chang; Centration Stability of a One-Piece Aspheric Diffractive Multifocal IOL. Invest. Ophthalmol. Vis. Sci. 2012;53(14):1375.
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To determine the centration stability of a one-piece aspheric diffractive multifocal IOL (ZMB00) in the first postoperative year.
A retrospective review was performed on 28 eyes following cataract surgery and implantation of a one-piece aspheric diffractive multifocal IOL (ZMB00). Computerized image analysis of serial pupil photographs provided relevant positional information. The data were grouped into four intervals for analysis: less than 2 months postoperative (mean 4 weeks, n = 10), 2 to 4 months postoperative (mean 13 weeks, n = 9), 4 to 6 months postoperative (mean 18 weeks, n = 10), and 6 to 12 months postoperative (mean 39 weeks, n = 8). Position and centration of the first Purkinje image (corneal vertex), pupil center, and IOL center from each time point were compared to their respective location on the first postoperative day.
Between the first postoperative day and the four follow-up intervals, a high positive correlation was found in the location of the corneal vertex (R = 0.99, 0.99, 1.00, and 0.98). A positive correlation was also found with the pupil size (R = 0.95, 0.91, 0.81, 0.67), as well as location relative to the corneal vertex (R = 0.96, 0.94, 0.95, 0.96), and the limbus centroid (R = 0.99, 0.96, 0.94, 0.90). Between the first postoperative day and the four follow-up intervals, the IOL center remained in close relative location to the pupil center (R = 0.85, 0.88, 0.88, 0.92), with a mean change of 0.15 ± 0.09, 0.14 ± 0.05, 0.18 ± 0.07, and 0.13 ± 0.05 mm. There was also a positive correlation between the IOL center and the corneal vertex (R = 0.75, 0.93, 0.97, 0.98), with a mean change in IOL position of 0.10 ± 0.06, 0.09 ± 0.07, 0.08 ± 0.07, and 0.10 ± 0.07 mm, for each of the intervals, respectively.
The centration of a one-piece aspheric diffractive multifocal IOL relative to the pupil center and corneal vertex remains stable throughout the first postoperative year.
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