April 2011
Volume 52, Issue 14
Free
ARVO Annual Meeting Abstract  |   April 2011
Cirrus And Spectralis Fourier-domain Oct In Epiretinal Membranes: Reproducibility And Ability To Detect Retinal Alterations
Author Affiliations & Notes
  • Isabel Pinilla
    Ophthalmology, Universitary Hospital Lozano Blesa, Zaragoza, Spain
    Aragones Institute of Health Science, Zaragoza, Spain
  • Elena Garcia-Martin
    Aragones Institute of Health Science, Zaragoza, Spain
    Ophthalmology, Miguel Servet Hospital, Zaragoza, Spain
  • Emilio Abecia
    Aragones Institute of Health Science, Zaragoza, Spain
    Ophthalmology, Miguel Servet Hospital, Zaragoza, Spain
  • Nicolas Cuenca
    Fisiologia Genetica y Microbiologia, Universidad de Alicante, Alicante, Spain
  • Miriam Idoipe
    Ophthalmology, Miguel Servet Hospital, Zaragoza, Spain
    Instituto Aragones de Ciencias de la Salud, Zaragoza, Spain
  • Javier Ascaso
    Ophthalmology, Universitary Hospital Lozano Blesa, Zaragoza, Spain
  • Pilar Calvo
    Ophthalmology, Miguel Servet Hospital, Zaragoza, Spain
  • Footnotes
    Commercial Relationships  Isabel Pinilla, None; Elena Garcia-Martin, None; Emilio Abecia, None; Nicolas Cuenca, None; Miriam Idoipe, None; Javier Ascaso, None; Pilar Calvo, None
  • Footnotes
    Support  PS09/01854, RETICS RD07/0062/0012
Investigative Ophthalmology & Visual Science April 2011, Vol.52, 1020. doi:
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      Isabel Pinilla, Elena Garcia-Martin, Emilio Abecia, Nicolas Cuenca, Miriam Idoipe, Javier Ascaso, Pilar Calvo; Cirrus And Spectralis Fourier-domain Oct In Epiretinal Membranes: Reproducibility And Ability To Detect Retinal Alterations. Invest. Ophthalmol. Vis. Sci. 2011;52(14):1020.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To evaluate the ability of Fourier-domain (FD) optical coherence tomography (OCT) to detect retinal alterations in epiretinal membrane (ERM) eyes. To test the intra-session reproducibility of macular thickness measurements in ERM and healthy subjects using Cirrus and Spectralis OCT.

Methods: : Two hundred and nine of 209 subjects (87 ERM patients and 122 healthy subjects) underwent three macular scans by the same experienced examiner using the Cirrus and Spectralis OCT technologies. Differences between healthy and ERM eyes were studied. The relationship between average thicknesses with both instruments was evaluated. Repeatability was studied by intra-class correlation coefficients and coefficients of variation (COV) for the nine areas corresponding to the Early Treatment Diabetic Retinopathy Study.

Results: : Macular thickness increase was detected in ERM eyes for all OCT parameters (p<0.05). Macular average thickness was 338.45 and 431.99 µm in ERM eyes using Cirrus and Spectralis, respectively. Changes in the morphology of the retinal layers were detected using both OCTs. Macular average thickness in ERM eyes as determined by both OCTs was correlated (r= 0.678; p<0.001), but differences were statistically significant (p=0.044). In ERM eyes, measurements showed a mean COV of 2.96% using Cirrus, 2.21% using Spectralis and 0.99% using Spectralis progression feature. Intra-class correlation coefficients were higher than 0.919.

Conclusions: : Significant differences exist in macular thickness measurements between Cirrus and Spectralis despite the high correlation of measurements between the two instruments. Fourier-domain OCT can be considered a valid device to detect alterations in ERM patients.

Keywords: imaging methods (CT, FA, ICG, MRI, OCT, RTA, SLO, ultrasound) • retina 
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