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Veronique Cloché, Marc André BIGARD, Laurent PEYRIN-BIROULET, Karine ANGIOI; Are Ocular Manifestations Predictive Of Ocular Inflammation In Inflammatory Bowel Disease? A Large Cross-sectional Survey. Invest. Ophthalmol. Vis. Sci. 2012;53(14):1433.
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Whether ocular symptoms predict the presence of inflammatory ocular diseases in inflammatory bowel diseases (IBD) is unknown.
All consecutive IBD patients seen in the Department of Gastroenterology (Nancy, University Hospital, France) between April 2009 and July 2011 were interviewed for this study using a pre-established questionnaire. This questionnaire was developed by the Departments of Gastroenterology and Ophthalmology. If the patient had at least one ocular symptom, he/she systematically underwent an ophthalmologic examination (visual acuity, Break-Up Time test, Schirmer test, slit-lamp exam with fundus examination).
This cross-sectional survey was completed by 306 patients: 169 were women (55.2%), 228 had Crohn’s disease (74.5%), 77 ulcerative colitis (25.2%) and 1 microscopic colitis (0.3%). Ninety-eight patients (32.02%) reported at least one ocular symptom: ocular irritation (56.8%), red eye (40.5%), blurred vision (37.8%), ocular pain (31.1%), progressive visual loss (34.4%), myodesopsia (23.3%), eyelid secretion (12.2%), dry eye (9.5%), watering (6.8%), diplopia (5.4%), metamorphopsia (4%), sudden visual loss (4%). Following ophthalmologic examination 41.9% patients had evidence of dry eye, 14.9% blepharitis and 1.4% scleritis. No uveitis was reported.
Ocular manifestations are frequent in IBD patients, but are very seldom associated with ocular inflammation. Systematic interviewing of IBD patients for ocular symptoms cannot be recommended in clinical practice.
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