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Savannah E. Baril, Suzanne K. Freitag; Incidence Of Benign And Malignant Eyelid Tumors At The Massachusetts Eye And Ear Infirmary Over One Year. Invest. Ophthalmol. Vis. Sci. 2012;53(14):1448.
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Eyelid lesions are the most common neoplasms encountered by ophthalmologists and encompass a variety of benign and malignant growths. The purpose of this study is to determine the diagnoses of the most frequently biopsied benign and malignant tumors evaluated at the ocular pathology department at a high volume institution.
A retrospective review and analysis was conducted of eyelid lesion specimens sent to the Massachusetts Eye and Ear Infirmary, Department of Ocular Pathology from September 14, 2010 to September 20, 2011. Final diagnosis of each specimen was then documented and the percentage of both malignant and benign lesions was calculated. The most frequently diagnosed lesions were also determined.
Information on 1364 total specimens was reviewed, and 689 (50%) were noted to be biopsies from the eyelid or surrounding tissues including the periorbital area, cheek, forehead, and nose. There were 574 (83%) benign lesions versus 115 (17%) malignant lesions. The most common benign lesions were inflammatory lesions including chalazia 106 (15%), papillomas 84 (12%), seborrheic keratosis 57 (8%), melanocytic nevi 55 (8%), and epidermoid and dermoid cysts 38 (5%). Of the subset of inflammatory lesions, 56 (52%) were chalazia. Basal cell carcinoma was the most frequently diagnosed malignant tumor 84 (13%), followed by squamous cell carcinomas 13 (2%), sebaceous gland carcinomas 6 (<1%), and malignant melanoma 5 (<1%). Of the malignant lesions, basal cell carcinoma represented 84 (73%) of the total malignant tumors.
At the Massachusetts Eye and Ear Infirmary, eyelid tumors were the predominant specimen type sent to the ocular pathology department. The majority of these lesions were benign. The incidence of basal cell carcinoma was significantly higher compared with that of squamous cell carcinoma, sebaceous gland carcinoma, and malignant melanoma. These statistics are consistent with published incidence rates of these respective lesions.
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