March 2012
Volume 53, Issue 14
Free
ARVO Annual Meeting Abstract  |   March 2012
Precision of ORA (Ocular Response Analyzer)
Author Affiliations & Notes
  • Susanne Goebels
    Department of Ophthalmology,
    University of Saarland, Homburg/Saar, Germany
  • Berthold Seitz
    Department of Ophthalmology,
    University of Saarland, Homburg/Saar, Germany
  • Achim Langenbucher
    Department of Experimental Ophthalmology,
    University of Saarland, Homburg/Saar, Germany
  • Footnotes
    Commercial Relationships  Susanne Goebels, None; Berthold Seitz, None; Achim Langenbucher, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 1532. doi:
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      Susanne Goebels, Berthold Seitz, Achim Langenbucher; Precision of ORA (Ocular Response Analyzer). Invest. Ophthalmol. Vis. Sci. 2012;53(14):1532.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To evaluate the repeatability of corneal hysteresis and corneal resistance measurements as well as the consistency of the 4 shots within each measurement using the ORA (Ocular Response Analyzer, Reichert Ophthalmic Instruments, USA) and to generate a pool of data of a normal population.

Methods: : A total of 45 eyes from 45 healthy volunteers without ocular pathologies and normal visual acuity were enrolled in this study. A sequence of five consecutive measurements was performed with each patient with the ORA. The biomechanical properties of the cornea in terms of corneal hysteresis (CH) and corneal resistance factor (CRF) were recorded, as well as the Goldmann-correlated IOP (IOPg) and cornea correlated IOP (IOPcc). The trend in each measurement sequence was analysed and Cronbach’s alpha was derived for the repeatability. The average of 4 shots within each measurement was compared with the best signal value (BSV) provided by the internal data processing of the ORA.

Results: : Mean value for CH was 11.58, BSV was 11.55. For CRF mean value was 11.21 and BSV was 11.28. No significant difference was found between average value and BSV of one measurement (p>0.05). No significant difference was found between average value and BSV of the five consecutive measurements, only IOPg showed a significant difference (p=0,017), average value of IOPg is higher than BSV. Within a sequence of 5 measurements for each individual, the average values of the four shots per measurement for IOPg and IOPcc are decreasing by 1.19 mmHg and 1.05 mmHg on average. The repeatability test revealed good results for CH, CRF (all α are higher than 0.9).

Conclusions: : The ORA provides beside intraocular pressure additional information about the biomechanical properties of the cornea such as hysteresis and resistance. It proofs to yield good repeatability for corneal hysteresis and resistance in normal subjects.

Keywords: cornea: clinical science 
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