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Zeev Zalevsky, Israel Margalit, Yevgeny Beiderman, Alon Skaat, Michael Belkin, Ralf-Peter Tornow, Vicente Mico, Javier Garcia; Remote and Continuous Monitoring of Intraocular Pressure Using Novel Photonic Principle. Invest. Ophthalmol. Vis. Sci. 2012;53(14):1972.
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© ARVO (1962-2015); The Authors (2016-present)
To present the initial experimental testing of a new measurement principle for continuous, remote non-contact and monitoring of intra-ocular pressure (IOP).
A photonic device involving a fast camera and a laser was tested in rabbit’s eyes for continuous remote monitoring of the IOP. The device is based on tracking the secondary speckle patterns trajectories produced by reflection of an illuminating laser beam from the iris, cornea or sclera. IOP fluctuations change the speckle distributions reflected from the rabbit’s tissues that are acting as a transducer element of the sensing system. The distribution is continuously measured and analysed. The device is inexpensive since it requires only a laser, a camera and a computer.The anterior chambers of the eyes were canulated by an anterior chamber maintainer connected to a saline infusion bag. The IOP was varied by changing the elevation of the bag in respect to the position of the eye. The changes in the speckle pattern was continually monitored and analysed.
Data from the photonic device were correlated with the IOP fluctuations resulting from raising and lowering the infusion bag. The measurements show a good correlation and sensitivity of the proposed device with IOP changes while providing a high precision measurement (5% estimated error) for the best experimental configuration. The results obtained via the photonic approach were also compared with a reference IOP measurement obtained with Goldmann tonometer.
The first experimental testing of a new photonic device has been performed with rabbits showing a promising new direction for remote and continuous monitoring of IOP. The system provides a high precision and non-invasive measurement method for IOP monitoring over prolonged periods.
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