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Sabrina Falah, Sarah Mrejen, José Alain Sahel, Michel Paques; Multimodal Imaging Of Choroidal Venous Abnormalities In Chronic Central Serous Chorioretinopathy. Invest. Ophthalmol. Vis. Sci. 2012;53(14):2115.
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To correlate choroidal and retinal abnormalities in chronic central serous chorioretinopathy.
Twelve patients (24 eyes) with chronic central serous chorioretinopathy with no prior treatment underwent indocyanine green angiography (ICGA) and enhanced depth optical coherence tomography (ED-OCT). Choroidal thickness was measured in the fovea. Dilated choroidal veins were identified on ICGA and ED-OCT.
The mean age of patients was 46 years. Ten patients were male (83%); and seven (58%) had bilateral disease. As compared to a control group, all patients had retrofoveolar choroidal thickening (496 microns), and focal choroidal thickening in the areas of dilated veins (number). ED-OCT analysis in the areas of dilated choroidal veins found an absence of overlying choriocapillaris in 16 eyes, a deformation of Bruch membrane in 12 eyes, and damage to the outer retina in 6 eyes.
Chronic CRSC is associated with dilated choroidal veins, which frequently colocalize with focal atrophy of the outer retina. This suggests that chronic CSCR may be a venous choroidal disorder with secondary ischemic damage to the retinal pigment epithelium.
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