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Thorunn S. Eliasdottir, Asbjorg Geirsdottir, Olafur Palsson, Sveinn H. Hardarson, Olof B. Olafsdottir, Jona V. Kristjansdottir, Einar Stefánsson; Retinal Vessel Oxygen Saturation In Healthy Individuals. Invest. Ophthalmol. Vis. Sci. 2012;53(14):2172.
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To determine the effects of age and gender on oxygen saturation in retinal vessels of healthy eyes.
The non-invasive retinal oximeter is based on a fundus camera (Oxymap ehf., Reykjavik Iceland). It simultaneously captures images of the retina at 600 and 570nm and estimates retinal vessel oxygen saturation. Mean oxygen saturation of hemoglobin was measured in retinal arterioles and venules of 111 healthy individuals, aged 19 - 75 years. Of the 111 participants, 42 (38%) were males (49±15 years, mean±SD) and 69 (62%) females (43±15 years).
The figure illustrates the relationship between retinal vessel oxygen saturation for males and females. The combined mean arteriolar oxygen saturation for both groups is 93.1±3.4% and 55.6±5.7 in venules.
Venular oxygen saturation decreases by approximately 1.5% for every ten years of age in males and 0.8% in females. There is no change in arteriolar oxygen saturation with age. The study provides normative data for retinal oximetry.
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