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Juan Carlos Ondategui Parra, Juan Antonio Martínez-Roda, Meritxell Vilaseca, Ferran Sanabria, Jaume Pujol; Use the Double-Pass Technique to Quantify Optical Quality and Intraocular Scattering in Amblyopic Eyes: A Pilot Study. Invest. Ophthalmol. Vis. Sci. 2012;53(14):3063.
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© ARVO (1962-2015); The Authors (2016-present)
To assess ocular optical quality (OQ) and intraocular scattering (IS) from double-pass (DP) images in patients with amblyopia.
We considered a group of 30 eyes of 30 subjects with treated amblyopia and a control group of 43 eyes of 27 healthy young subjects. Mean ages (± SD [range]) were of 9.90 ± 3.60 (8.62 to 10.93 yr.) for the amblyopic group and 7.13 ± 2.56 (5.71 to 8.55 yr.) for the control group. DP images with a pupil diameter of 4 mm were taken using a clinical instrument (OQAS, Visiometrics SL, Spain) (Güell et al. J Cataract Refr Surg 2004), and several parameters related to the OQ and IS of the eye (Strehl ratio, OQAS values [OV] at contrasts 100%, 20% and 9%, and Objective Scatter Index [OSI]) (Martínez-Roda et al. Clin Exp Optom 2011; Artal et al. Plos 2011) were computed. Moreover, we measured the best spectacle-corrected visual acuity (BSCVA) with a standard logMAR chart.
LogMAR BSCVA for amblyopic eyes was 0.12 ± 0.11 and for control group -0.05 ± 0.11. OQ and IS parameters for amblyopic eyes were: Strehl ratio 0.19 ± 0.08; OV 100% 0.97 ± 0.39; OV 20% 1.03 ± 0.47; OV 9% 1.10 ± 0.55; and OSI 1.34 ± 1.11. For the control group we obtained: Strehl ratio 0.25 ± 0.07; OV 100% 1.41 ± 0.25, OV 20% 1.49 ± 0.36, OV 9% 1.54 ± 0.44; and OSI 0.58 ± 0.20. The results reported statistically significant differences (p<0.05) in the majority of the ocular quality parameters when amblyopic eyes were compared to those belonging to the control group, even in those already treated and with normal visual acuity values.
We found lower OQ and IS values in treated amblyopic eyes compared with those belonging to the control group. However conventional visual acuity tests did not show differences between groups. Future work will be focused on analysing the OQ and IS variations between treated and untreated amblyopic eyes, and on exploring the usefulness of retinal imaging analysis for objective diagnosis and treatment of patients with amblyopia.
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