March 2012
Volume 53, Issue 14
Free
ARVO Annual Meeting Abstract  |   March 2012
Quantitatively Characterizing Irido-Trabecular Contact (ITC) Using Anterior Segment Optical Coherence Tomography (AS-OCT) Images
Author Affiliations & Notes
  • Mansoor Mughal
    Ophthalmology, Robert Cizik Eye Clinic, Houston, Texas
  • Leslie Pfeiffer
    Ophthalmology, Robert Cizik Eye Clinic, Houston, Texas
  • Alice Z. Chuang
    Ophthalmology, Robert Cizik Eye Clinic, Houston, Texas
  • Laura Baker
    Ophthalmology, Robert Cizik Eye Clinic, Houston, Texas
  • Nicholas Bell
    Ophthalmology, Robert Cizik Eye Clinic, Houston, Texas
  • Robert M. Feldman
    Ophthalmology, Robert Cizik Eye Clinic, Houston, Texas
  • Footnotes
    Commercial Relationships  Mansoor Mughal, None; Leslie Pfeiffer, None; Alice Z. Chuang, None; Laura Baker, None; Nicholas Bell, None; Robert M. Feldman, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 3276. doi:
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    • Get Citation

      Mansoor Mughal, Leslie Pfeiffer, Alice Z. Chuang, Laura Baker, Nicholas Bell, Robert M. Feldman; Quantitatively Characterizing Irido-Trabecular Contact (ITC) Using Anterior Segment Optical Coherence Tomography (AS-OCT) Images. Invest. Ophthalmol. Vis. Sci. 2012;53(14):3276.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract
 
Purpose:
 

To determine the relationship between ITC measured using AS-OCT and gonioscopy

 
Methods:
 

A retrospective chart review of gonioscopy and AS-OCT images (Casia SS-1000, Tomey, Nagoya, Japan) between September 2010 - August 2011. Eyes which had previous ocular surgery or intraocular injections were excluded. Age, sex, race, and Shaffer gonioscopy grade were recorded. 2D scan images were reviewed by 2 readers using proprietary software to determine the scleral spur location (SS) and the end of the angle opening (EAO) at 0, 90, 180 and 270 degrees. The mean SS and EAO locations were used as the final locations. ITC was defined as EAO more than 80 µm central from the SS. Trabecular iris contact length (TICL) was defined as the distance from SS to EAO if ITC was observed. Frequency (%) of ITC and mean (± standard deviation) of TICL were summarized for each gonioscopy grade by each quadrant.

 
Results:
 

Fifty four eyes from 54 patients with a mean age of 52 ± 16 years were included. Thirty one (57%) were female, 32 (60%) were white, 12 (22%) were Hispanic and 6 (11%) where black

 
Conclusions:
 

AS-OCT measurements of ITC corresponded with gonioscopy. TICL was typically approximately 500 microns in length in eyes with narrow angles. It is possible that ITC in gonioscopically open angles may represent the presence of iris processes, which do not extend as far anteriorly  

 
Keywords: anterior segment • imaging/image analysis: clinical • trabecular meshwork 
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