March 2012
Volume 53, Issue 14
Free
ARVO Annual Meeting Abstract  |   March 2012
Placement of ProKera for Recurrent Corneal Erosion
Author Affiliations & Notes
  • Yukan Huang
    Ocular surface center, Miami, Florida
  • Ahmad Kheirkhah
    Ocular surface center, Miami, Florida
  • Scheffer C.G. Tseng
    Ocular surface center, Miami, Florida
  • Footnotes
    Commercial Relationships  Yukan Huang, None; Ahmad Kheirkhah, None; Scheffer C.G. Tseng, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 3569. doi:
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      Yukan Huang, Ahmad Kheirkhah, Scheffer C.G. Tseng; Placement of ProKera for Recurrent Corneal Erosion. Invest. Ophthalmol. Vis. Sci. 2012;53(14):3569.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : Transplantation of cryopreserved amniotic membrane has been successful in treating a number of ocular surface diseases. Placement of cryopreserved amniotic membrane as a temporary bandage is another mode for promoting corneal epithelial wound healing by suppressing inflammation and scarring. We would like to investigate the efficacy of placement of sutureless cryopreserved amniotic membrane in eyes presenting atypical pictures of recurrent corneal erosion (RCE).

Methods: : 5 eyes of 4 patients presented persistent lid margin discomfort especially upon blinking. After examination, RCE was diagnosed. Following epithelial debridement, ProKera (Bio-Tissue, Miami, Florida) was placed with prophylactic topical antibiotics and steroid.

Results: : All eyelids did not exhibit any noticeable pathology. However, the lid discomfort was partially aborted by topical anesthetics. All except for one had no corneal epithelial staining. Although lid discomfort was the primary complaint, all corneas exhibited loose and wrinkled epithlelium upon direct compression by a Weckcel. Rapid epithelialization was noted within one week after placement of ProKera, resulting in resolution of eyelid discomfort and a stable corneal epithelium.

Conclusions: : RCE can present with lid discomfort as an atypical symptom. Corneal epithelial debridement in conjunction of placement of ProKera can be a safe and efficacious measure for alleviating this type of RCE.

Keywords: cornea: epithelium • eyelid • wound healing 
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