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Ricardo Vargas, Mauricio Rivera-Narvaez, Arturo J. Ramirez-Miranda, Alejandro Navas, Zoraida Espinosa-Mattar, Angie De La Mota, Tito Ramirez-Luquin, Aida Jimenez-Corona, Enrique O. Graue; Comparison Of Corneal Thickness Measurements Between Scanning Slit Beam Technology, Optical Coherence Tomography, And 3 Scheimpflug Imaging Systems. Invest. Ophthalmol. Vis. Sci. 2012;53(14):4035.
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© ARVO (1962-2015); The Authors (2016-present)
To compare Central Corneal Thickness (CCT) and Corneal Thinnest Point (CTP) measurements by five
Scanning-Slit Technology (SST), three Scheimpflug Imaging Systems (SIS), and optical coherence tomography (OCT).Methods: This was a prospective single-center study, of 84 eyes of 42 patients were were examined with the Orbscan II (SST) the Pentacam, Galilei, and Sirius systems (all three SIS), and the Visante (OCT). To assess the intraobserver, interobserver and interdevice reproducibility of the 5 systems, all the eyes were examined 2 times by 2 independent observers and the reliability coefficient was calculated using Cronbach alpha-test.
The mean CCTs were as follows (microns): 532.74 ± 50.41 μm (Orbscan), 538.50 ± 44.58 μm (Pentacam), 557.82 ± 42.84 μm (Galilei), 556.59 ± 68.29 μm (Sirius), 521.76 ± 59.03 μm (Visante). Mean CTP were as follows (microns): 523.05 ± 52.13 μm (Orbscan), 534.04 ± 44.91 μm (Pentacam), 544.34 ± 43.79 μm (Galilei), 517.73 ± 47.87 μm (Sirius). Intraobserver Cronbach alpha-test showed a very good reliability coefficient (>0.90) in both measurements by SST, and the three SIS, but not for the OCT (less 0.80). Inter observer Cronbach alpha-test showed a good reliability coefficient (>0.80) in all the systems. Using the Pentacam as reference the Interdevice reliability coefficient was good for the rest of the devices (>0.80).
Corneal Central Thicknes and Corneal Thinnest Point readings with the SST, the three SIS systems showed very good correlation and high reproducibility. Although differences between the intra observer measurements with the OCT were significant, there was good correlation and agreement in the interdevice analysis.This Results show that the CCT and CTP measurements with several systems can be used interchangeably, and can be delegated to technical personnel.
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