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Tatsuya Yoshitake, Kenji Yamashiro, Masahiro Miyake, Yumiko Akagi-Kurashige, Akio Oishi, Akitaka Tsujikawa, Masanori Hangai, Nagahisa Yoshimura; Shapes of Posterior Pole Associated with Retinoschisis in Highly Myopic Eyes. Invest. Ophthalmol. Vis. Sci. 2012;53(14):4455.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate the shape of posterior pole in association with retinoschisis and retinal detachment (RD) secondary to high myopia.
Forty seven patients aged ≥40 years with an axial length ≥26.5 mm in both the eyes were studied. Of the 58 eyes that underwent 12 lines of 9 mm-length radial scanning with spectral-domain optical coherence tomography (OCT) centering at the fovea, 31 eyes showed retinoschisis and/or RD, whereas 27 eyes did not. Three-dimensional images of the posterior pole were constructed from the OCT data by using image analysis software (Canon Retina View); the retinal pigment epithelium (RPE)/Bruch’s membrane boundaries were detected in each B-scan image, and twelve boundaries of each eye constituted the shape of the posterior pole. In order to compare the shape of the posterior pole between the eyes with retinoschisis/RD and those without (control group), the volumes of the space between RPE surface and horizontal plane at the heights of 0.1, 0.3, and 0.5 mm from the bottom of the posterior pole were calculated.
Although no significant difference was observed in the axial length between the two groups (p = 0.11), the volume at the height of 0.1 mm was significantly smaller in the group with retinoschisis/RD (0.17 ± 0.089mm³) than that in the control group (0.22 ± 0.11mm³, p = 0.032). However, no significant difference was observed between the two groups for the volume at the height of 0.3 mm (1.86 ± 0.071 mm³ vs.2.08 ± 0.073 mm³, p = 0.27), and at 0.5 mm (4.95 ± 1.02mm³ vs. 5.29 ± 1.51mm³, p = 0.40).
Only the volume at the height of 0.1 mm showed a significant difference. This could suggest that the shape of posterior pole in the group with retinoschisis/RD is sharp-pointed as compared with that of the control group, particularly around the fovea. Therefore, the distinctive shape of the posterior pole may contribute to the onset of retinoschisis/RD in highly myopic eyes.
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