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Leila El Matri, Ahmed Chebil, Leila Largueche, Mejda Bouladi, Fedra Kort, Salma Touati; SD OCT In Cystoid Macular Edema Associated With Retinitis Pigmentosa. Invest. Ophthalmol. Vis. Sci. 2012;53(14):4579.
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© ARVO (1962-2015); The Authors (2016-present)
To determine the prevalence of cystoid macular edema (CME) in retinitis pigmentosa (RP) patients using spectral optical coherence tomography (SD OCT) and to assess the correlation between macular morphology of CME and visual acuity.
One hundred and ninety-six eyes of 100 patients with RP were examined with the spectral optical coherence tomography (3D-OCT-2000). The transverse and vertical lengths of the cystoid space and the status of the inner segment/outer segment junction (IS/OS) (Grade 1: absent, Grade 2: discontinuous, or Grade 3: distinct)were evaluated. Correlation between visual acuity and each of the measurements were examined.
Of the 196 eyes, 31 showed CME in both eyes (15.8%), while 11 showed CME in at least one eye (5.6%). Total retinal thickness was not correlated with visual acuity. There was a correlation between the transverse length of the cystoids space and visual acuity (p=0.044). The logMAR visual acuity in the IS/OS absent group (0.77±0.53) was worse than the one seen in the IS/OS discontinuous (0.31±0.22) or IS/OS distinct groups (0.09±0.21) (P<0.001).
It would be useful to screen RP patients by OCT for the possible presence of CME. The status of IS/OS and the transverse length of the cystoids space are the essential parameters that need to be examined.
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