March 2012
Volume 53, Issue 14
Free
ARVO Annual Meeting Abstract  |   March 2012
Relationships between Central Choroidal Thickness and Visual Function in Retinitis Pigmentosa
Author Affiliations & Notes
  • Ryuta Kimoto
    Ophthalmolory, Chiba University, Chiba-shi, Japan
  • Akira Hagiwara
    Ophthalmolory, Chiba University, Chiba-shi, Japan
  • Ken Kumagai
    Ophthalmolory, Chiba University, Chiba-shi, Japan
  • Toshiyuki Oshitari
    Ophthalmolory, Chiba University, Chiba-shi, Japan
  • Takeshi Sugawara
    Ophthalmolory, Chiba University, Chiba-shi, Japan
  • Shuichi Yamamoto
    Ophthalmolory, Chiba University, Chiba-shi, Japan
  • Footnotes
    Commercial Relationships  Ryuta Kimoto, None; Akira Hagiwara, None; Ken Kumagai, None; Toshiyuki Oshitari, None; Takeshi Sugawara, None; Shuichi Yamamoto, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 4583. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Ryuta Kimoto, Akira Hagiwara, Ken Kumagai, Toshiyuki Oshitari, Takeshi Sugawara, Shuichi Yamamoto; Relationships between Central Choroidal Thickness and Visual Function in Retinitis Pigmentosa. Invest. Ophthalmol. Vis. Sci. 2012;53(14):4583.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose: : To study the relationships between the central choroidal thickness and visual function in retinitis pigmentosa (RP).

Methods: : Thirty-eight eyes of 25 patients with typical RP were examined. The length of the IS/OS line, the central choroidal thickness (CCT), and choriocapillary thickness, i.e., distance between retinal pigment epithelium (RPE) and inner border of medium-large choroidal vessels, were measured by enhanced depth imaging with spectral domain OCT. The best-corrected visual acuity (BCVA) and retinal sensitivity within the central 10 degrees determined by microperimetry were also measured.

Results: : The average CCT in eyes with RP was significantly thinner than that in healthy normal Japanese (258±66 μm vs. 354±111 μm). There was no significant correlation between CCT and BCVA (P=0.89), and the CCT and retinal sensitivity (P=0.62). There was a weak but significant correlation between the CCT and length of the IS/OS line (rs = -0.38; P=0.02). The length of the IS/OS line of patients with retinal sensitivities ≥10dB were significantly longer than those with <10dB. The choriocapillary of patients with CCT <250 μm and retinal sensitivities ≥10 dB was thicker than those with CCT ≥250 μm and retinal sensitivities <10 dB.

Conclusions: : The central choroid was significantly thinner in RP patients than normal controls, however, the thickness of choriocapillaris may have more influence on the visual function than the choroidal thickness itself.

Keywords: imaging/image analysis: clinical • choroid • retina 
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×