March 2012
Volume 53, Issue 14
Free
ARVO Annual Meeting Abstract  |   March 2012
Anterior Chamber Aqueous Flare In Pseudoexfoliation Syndrome
Author Affiliations & Notes
  • Sonia Attia
    Ophthalmology, University hospital Fattouma Bourguiba, Monastir, Tunisia
  • Sana Khochtali
    Ophthalmology, University hospital Fattouma Bourguiba, Monastir, Tunisia
  • Nessrine Abroug
    Ophthalmology, University hospital Fattouma Bourguiba, Monastir, Tunisia
  • Ilhem Kacem
    Ophthalmology, University hospital Fattouma Bourguiba, Monastir, Tunisia
  • Sonia Zaouali
    Ophthalmology, University hospital Fattouma Bourguiba, Monastir, Tunisia
  • Salim Ben Yahia
    Ophthalmology, University hospital Fattouma Bourguiba, Monastir, Tunisia
  • Moncef Khairallah
    Ophthalmology, University hospital Fattouma Bourguiba, Monastir, Tunisia
  • Footnotes
    Commercial Relationships  Sonia Attia, None; Sana Khochtali, None; Nessrine Abroug, None; Ilhem Kacem, None; Sonia Zaouali, None; Salim Ben Yahia, None; Moncef Khairallah, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 5047. doi:
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      Sonia Attia, Sana Khochtali, Nessrine Abroug, Ilhem Kacem, Sonia Zaouali, Salim Ben Yahia, Moncef Khairallah; Anterior Chamber Aqueous Flare In Pseudoexfoliation Syndrome. Invest. Ophthalmol. Vis. Sci. 2012;53(14):5047.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : To evaluate anterior chamber aqueous flare (ACAF) in subjects with pesudoexfoliation (PEX) syndrome.

Methods: : The study included 124 eyes from 62 consecutive patients divided into the 2 following groups: group 1 (pesudoexfoliation glaucoma, [PEXG]) and group 2 (normotensive individuals with PEX syndrome). The study also included 32 age-matched control patients. All patients underwent complete ophthalmic examination with evaluation of intraocular pressure and cup/disc ratio. The ACAF was measured with laser flare photometry.

Results: : ACAF values in PEXG eyes ranged from 8.66 photon counts/ms to 57.13 photon counts/ms (mean +/- SD, 23.57 +/- 12.80 photon counts/ms; 95% confidence interval [CI]). In PEX syndrome eyes and control group, values were between 1.00 photon counts/ms and 24.6 photon counts/ms (mean +/- SD, 14.05 +/- 5.93 photon counts/ms; 95% confidence interval [CI]), and 5.80 photon count/ms and 12.80 photon count/ms (mean +/- SD, 8.61 +/- 1.87; 95% confidence interval [CI]), respectively. ACAF was significantly higher in PEXG group compared to PEX syndrome group (p= 0.046). There was no correlation between the ACAF and the cup/disc ratio in patients with PEXG.

Conclusions: : Laser flare photometry is a fast, noninvasive, and quantitative method to evaluate the increase in aqueous flare intensity. A high ACAF value might be a predictor of the development of glaucoma in patients with PEX syndrome.

Keywords: aqueous • anterior chamber • inflammation 
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