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Sonia Attia, Sana Khochtali, Nessrine Abroug, Ilhem Kacem, Sonia Zaouali, Salim Ben Yahia, Moncef Khairallah; Anterior Chamber Aqueous Flare In Pseudoexfoliation Syndrome. Invest. Ophthalmol. Vis. Sci. 2012;53(14):5047.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate anterior chamber aqueous flare (ACAF) in subjects with pesudoexfoliation (PEX) syndrome.
The study included 124 eyes from 62 consecutive patients divided into the 2 following groups: group 1 (pesudoexfoliation glaucoma, [PEXG]) and group 2 (normotensive individuals with PEX syndrome). The study also included 32 age-matched control patients. All patients underwent complete ophthalmic examination with evaluation of intraocular pressure and cup/disc ratio. The ACAF was measured with laser flare photometry.
ACAF values in PEXG eyes ranged from 8.66 photon counts/ms to 57.13 photon counts/ms (mean +/- SD, 23.57 +/- 12.80 photon counts/ms; 95% confidence interval [CI]). In PEX syndrome eyes and control group, values were between 1.00 photon counts/ms and 24.6 photon counts/ms (mean +/- SD, 14.05 +/- 5.93 photon counts/ms; 95% confidence interval [CI]), and 5.80 photon count/ms and 12.80 photon count/ms (mean +/- SD, 8.61 +/- 1.87; 95% confidence interval [CI]), respectively. ACAF was significantly higher in PEXG group compared to PEX syndrome group (p= 0.046). There was no correlation between the ACAF and the cup/disc ratio in patients with PEXG.
Laser flare photometry is a fast, noninvasive, and quantitative method to evaluate the increase in aqueous flare intensity. A high ACAF value might be a predictor of the development of glaucoma in patients with PEX syndrome.
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