March 2012
Volume 53, Issue 14
Free
ARVO Annual Meeting Abstract  |   March 2012
Repeatability of Intraocular Pressure Measurements in sitting and supine Position with a hand-held Prototype of PASCAL™ Dynamic Contour Tonometer
Author Affiliations & Notes
  • Marc Toeteberg-Harms
    Department of Ophthalmology, UniversityHospital Zurich, Zurich, Switzerland
  • Caterina Schweier
    Department of Ophthalmology, UniversityHospital Zurich, Zurich, Switzerland
  • Christoph Kniestedt
    Department of Ophthalmology, UniversityHospital Zurich, Zurich, Switzerland
  • Jens Funk
    Department of Ophthalmology, UniversityHospital Zurich, Zurich, Switzerland
  • Footnotes
    Commercial Relationships  Marc Toeteberg-Harms, None; Caterina Schweier, None; Christoph Kniestedt, None; Jens Funk, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science March 2012, Vol.53, 5071. doi:
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      Marc Toeteberg-Harms, Caterina Schweier, Christoph Kniestedt, Jens Funk; Repeatability of Intraocular Pressure Measurements in sitting and supine Position with a hand-held Prototype of PASCAL™ Dynamic Contour Tonometer. Invest. Ophthalmol. Vis. Sci. 2012;53(14):5071.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose: : PASCAL Dynamic Contour Tonometer (DCT) has proven its accuracy. The intraocular pressure (IOP) measured by DCT is less influenced by corneal biomechanical properties and central corneal thickness (CCT) compared to Goldmann-Applanation-Tonometry. At the moment, commercially only a slit lamp mounted DCT is available. In some patients one can only examine them in supine position. In this study we investigated the prototype of a hand held-DCT (hh-DCT) and calculated repeatability of IOP-measurements in sitting and supine position.

Methods: : IOP was first measured with PASCAL hh-DCT three times in sitting position in 28 eyes of 14 healthy volunteers. After lying down for 10min, IOP was measured again three times in supine position.

Results: : Mean age was 46.3±15.9years, CCT 540±34µm, refractive error (RE) less than ±5.0D spherical and ±1.5D cylindrical and axial length (AL) 24.01±1.43mm. IOP was 15.5±2.1 mmHg in sitting and 19.6±1.8mmHg in supine position, respectively (p<0.001). Multivariate analysis of variance shows a dependency on axial length bit not on age, CCT and RE. Bland-Altman analysis shows good repeatability of re-measurement between the first and the last of three IOP measurements in sitting (bias +0.2mmHg, 95% limits of agreement -3.4 - 3.7mmHg) as well as in supine (bias -0.1mmHg, 95% limits of agreement -3.1 - 2.9mmHg) position.

Conclusions: : Our results show that with the PASCAL hh-DCT IOP is higher in supine compared to sitting position. This is important because sometimes it is impossible to use a slit lamp mounted DCT device. In those cases, the higher reading of IOP in supine position of approximately 4.1mmHg on average in comparison to the IOP reading in sitting position of a patient must be taken into account. Bland-Altman-Analysis shows good agreement between repeated IOP measurement in sitting as well as in supine position, thus indicating good reproducibility of the hh-DCT device.

Clinical Trial: : http://www.clinicaltrials.gov NCT01325324

Keywords: intraocular pressure 
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