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Wilma L. Barboza, Francisco E. Lima, Luciana M. Alencar, Marcelo Hatanaka, Ricardo Suzuki, Remo Susanna, Jr.; Evaluation Of Iop After Endoscopic Cyclophotocoagulation With The Water Drinking Test And The Ibopamine Test. Invest. Ophthalmol. Vis. Sci. 2012;53(14):5082.
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© ARVO (1962-2015); The Authors (2016-present)
To compare the intraocular pressure (IOP) rise after 2% Ibopamine Test (IT) and water drinking test (WDT) in glaucomatous eyes after successful endoscopic cyclophotocoagulation (ECP)
This study enrolled 24 eyes of 24 patients after successful ECP with controlled IOPs without the need for medication. All individuals had been referred for ECP due to refractory glaucoma and IOP > 30mmHg despite maximum therapy. After baseline IOP measurements, Ibopamine 2% drops were instilled twice (5 minute interval) and IOP was measured at15, 30 and 45 minutes. With at least 48 hours of interval, patients underwent the WDT by drinking 800ml of water, IOP was measured before water ingestion and at 15, 30 and 45 minutes after the ingestion. The main outcomes measured were mean IOP peaks of each test. Paired t-test was used to compare peaks between tests
The average interval between the ECP and both tests was 18.66 months (13 to 31 months). Mean baseline IOP was 9.58+/-2.28 mmHg (8 to 12 mmHg) before the WDT and 9.54 +/-1.66 mmHg (range 7 to 12 mmHg) before the IT (p=0.84). The mean IOP peak was 13.45+/-4.0mmHg (8 to 24mmHg) for the WDT (p<0.001) and 11.75 +/- 3.53mmHg (7 to 22 mmHg) for the IT (p<0.001). There was a significant difference in the IOP elevation observed by each test (p=0.043) with an average difference of 2.16+/-4.96 mmHg
Both the Ibopamine Test and the Water Drinking Test increased the IOP in eyes submitted to successful endoscopic cyclophotocoagulation. However, there was a significant difference between the tests, with greater elevation observed on the water drinking test
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