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Seung-Young Yu, Ji-Sang Han, Kook-Young Kim, Hyung-Woo Kwak; Association between Fundus Autofluorescence with foveal microstructure and visual outcome after successful surgical detachment repair. Invest. Ophthalmol. Vis. Sci. 2012;53(14):5801.
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© ARVO (1962-2015); The Authors (2016-present)
To evaluate the visual prognosis and foveal microstructural changes in optical coherence tomography (OCT) after successful reattachment surgery in macula-off rhegmatogenous retinal detachment (RRD).
We retrospectively studied 24 eyes of 24 patients who underwent retinal reattachment surgery for macular-off RRD and were followed up for more than 6 months from April 2009 to March 2010 were enrolled in this study. The integrity of fovea microstructure was studied using spectral domain optical coherence tomography (SD OCT). The study eyes were categorized into three groups; A group with intact inner and outer segment (IS/OS) and intact external limiting membrane (ELM), B group with disrupted IS/OS and intact ELM, C group with disrupted IS/OS and disrupted ELM. We divided the study eyes again into two groups according to the autofluorescence (AF); Normal AF and increased AF.
Mean BCVA in disrupted ELM group at 1 month, 3 months and 6 months were 1.14 ± 0.72, 1.11 ± 0.41 and 1.18 ± 0.47, while 0.60 ± 0.43, 0.49 ± 0.45 and 0.44 ± 0.46 in intact ELM group. Improvement of BCVA was significantly different between two groups at 1 month (p=0.029), 3 months (p=0.004) and 6 months (p=0.013) after surgery. Mean BCVA in disrupted IS/OS group at 1 month, 3 months and 6 months were 0.84 ± 0.65, 0.86 ± 0.56 and 1.07 ± 0.64, while 0.56 ± 0.31, 0.38 ± 0.30 and 0.36 ± 0.31 in intact IS/OS group. Improvement of BCVA was not significantly different between two groups at 1 month (p=0.411), but significantly different at 3 months (p=0.010) and 6 months (p=0.004) after surgery. Improvement of BCVA according to autofluorescence was not significantly different between two groups.
After anatomically successful RRD surgery, integrity of ELM or IS/OS signals in OCT may predict visual prognosis.
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